Haole koa 40%

Question 1

What is haole koa? taxonomy, invasive?

Answer 1

invasive plant species in arid parts of HI, look like pea pods= Leucana leucocephala

Question 2

Toxic principle (haole koa)

Answer 2

Leaves and seeds contain glucoside mimosine it inhibits DNA synthesis, reduced thyroid function= goiter (depresses uptake of iodine), infertility.

Question 3

Pathophysiology of toxins (haole koa)

Answer 3

Ingestion of large amounts of haole koa occurs most often in times of draught> ruminants can degrade toxins, can slowly intro to sheep/ goats to develop tolerance, can add iron salts to reduce toxicity + soak in water or drying to reduce toxic effects.

Question 4

Clinical signs (haole koa)

Answer 4

primarily causes hair loss> horses and young cattle +/- horizontal cracked hooves.

Question 5

Treatment (haole koa)

Answer 5

Eliminate or reduce exposure, alternative forages, slow intro to reduce risk of clinical signs.