Chlamydophilia sp 40%

Question 1

what is Chlamydophila (chlamydia)

Answer 1

gram negative, obligate intracellular bacteria
C. abortus (sheep/ goats)- late stage abortions, placental lesions (thickened, yellow/brown exudate)- enzootic abortions in ewes
C. caviae (guinea pigs)- ocular, urogenital infections
C. felis (cats)- conjunctivitis, URI, bronchopneumonia
C. muriadarun (rodents)- pneumonia in colonies
C. Pecorum (cattle)- multisystem disease
C. pneumoniae (human)- respiratory disease
C. trachomatis (humans, pigs, birds)- urogenital infections
C. suis (swine)- most prevalent, multiple system infections
C. psittaci (parrots)- avian chlamydiosis

Question 2

Transmission (chlamydia)

Answer 2

close contact or aerosol contact, during parturition, aerosol transmission- zoonosis

Question 3

Clinical signs (chlamydia)

Answer 3

species dependent- general inflammation, respiratory disease, abortions/ infertility, polyarthritis, conjunctivitis, nasal discharge, sneezing, fever, lethargy and dyspnea/ pneumonia.
Birds- Hematologic changes most often present are anemia and leukocytosis with heterophilia and monocytosis. Plasma bile acids, AST, LDH, and uric acid may be increased.

Question 4

Diagnosis (chlamydia)

Answer 4

tissue inclusions on histo, cell culture, IFA, PCR, culture

Question 5

Treatment (chlamydia)

Answer 5

oral doxycycline or tetracycline - chase with water
clavamox
macrolides or fluoroquinilones
topical oxytetracyline or erythromycin
treat for 4 weeks

Question 6

prevention (chlamydia)

Answer 6

vaccine (non core) for ungulates, cats

inactivated by detergents (wash hands)

Question 7

zoonotic (chlamydia)

Answer 7

very unlikely but yes- wash hands, avoid contact with infected tissues, PPE