Hand Rheumatology Flashcards
A 55-year-old woman comes to the office with progressive swelling around the wrist. Tendon rupture is suspected. Which of the following tendons is most likely to rupture in a patient with rheumatoid arthritis? A) Extensor digitorum communis B) Extensor digitorum manus C) Extensor pollicis longus D) Flexor digitorum profundus E) Flexor pollicis longus
A) Extensor digitorum communis
Mechanisms for tendon rupture in rheumatoid arthritis
- Constant wear over a bony prominence leading to attrition, direct invasion of the tendon
- Synovitis and ischemic necrosis of the tendon secondary to proliferative synovitis.
Clinical presentation after tendon rupture in rheumatoid arthritis
When tendon rupture occurs, it is usually painlessand results only after trivial use of the tendon. In some patients, the functional deficit is not noticeable immediately, leading to a delay in diagnosis.
Tendons most commonly involved in rheumatoid arthritis tendon rupture
The tendons involved most commonly are the extensor tendons on the ulnar aspect of the hand. Once the ulnar extensors rupture, the progression will advance radially to the remaining extensors.
Complications that can be confused with extensor tendon rupture in rheumatoid arthritis
These include metacarpophalangeal joint dislocation, extensor tendon displacement between the metacarpal heads, and paralysis of the common extensor muscle
1st and 2nd most common tendon rupture of the hand in rheumatoid arthritis
1st: Extensor tendons on the ulnar aspect of the hand
2nd: Extensor pollicis longus
Clinical presentation of extensor policies longs rupture in rheumatoid arthritis
Extensor pollicis longus rupture is the second most common rupture found in rheumatoid disease of the hand, and it is diagnosed by an inability to extend the interphalangeal joint of the thumb.
Treatment of tendon ruptures in rheumatoid arthritis
Treatment of tendon ruptures involves tendon grafts and transfers, as well as removal of bony prominences when appropriate.
A 76-year-old woman with rheumatoid arthritis comes to the office because of a 2-month history of difficulty flexing the index finger of the left hand. She says that when she flexes the finger, a painful snapping sensation occurs. Physical examination shows fullness of the flexor tendon at the level of the A1 pulley. Which of the following is the most appropriate surgical treatment?
A) Release of the A1 pulley alone
B) Release of the A1 pulley and stair-step expansion repair of the pulley
C) Removal of the entire flexor digitorum superficialis tendon
D) Routing of the A1 pulley under the flexor tendons
E) Synovectomy and debridement of the flexor tendons
E) Synovectomy and debridement of the flexor tendons
This examination and history of the patient described are consistent with a diagnosis of trigger finger. Trigger fingers are common in patients with rheumatoid arthritis and are related to intratendinous nodules, as well as synovial inflammation common with rheumatoid arthritis.
Trigger fingers in rheumatoid arthritis
Trigger fingers are common in patients with rheumatoid arthritis and are related to intratendinous nodules, as well as synovial inflammation common with rheumatoid arthritis.
Initial management of trigger finger in rheumatoid arthritis
Typical management of trigger fingers consists of conservative treatment with steroid injection as the initial course of action. This is true in patients with rheumatoid arthritis as well.
Surgical management for trigger finger in rheumatoid arthritis
The most appropriate surgical treatment is flexor tenosynovectomy and removal of intratendinous nodules.
If this is unsuccessful, removal of a slip of the superficialis tendon is appropriate.
Normally, division of the A1 pulley results in excellent success, but the A1 pulley should never be divided in a rheumatoid patient.
When is surgical treatment indicated for trigger finger?
When patients have failed conservative treatment with steroid injection, surgery is indicated.
A1 pulley in rheumatoid arthritis patients
Normally, division of the A1 pulley results in excellent success. However, in the case of a rheumatoid patient, the A1 pulley is often the only remaining structure preventing ulnar drift of the tendons and joints. As a result, the A1 pulley should never be divided in a rheumatoid patient.
A 23-year-old man has decreased grip strength in the right hand 4 years after sustaining a volar forearm laceration. A photograph of the hand posture is shown. No nerve repair was performed at the time of injury. During testing with the metacarpophalangeal (MCP) joints blocked, the patient attempts to extend the interphalangeal (IP) joints (Bouvier maneuver) but is unable to do so. Passively, the IP joints can be extended. Tendon transfer to improve grip strength is planned. During this procedure, the tendon is best inserted distally at which of the following locations? A ) A2 pulley B ) Dorsal apparatus lateral band C ) MCP joint volar plate D ) Palmar fascia E ) Proximal phalanx
B ) Dorsal apparatus lateral band
The patient described has a classic case of ulnar nerve palsy. If MCP hyperextension is passively prevented by dorsalpressure, the extensor digitorum communis may be able to extend the middle and distal phalanges (Bouvier maneuver). If this cannot be done, then the tendon transfer insertion is into the dorsal apparatus.
A 30-year-old man sustains a laceration to the radial nerve at the mid-humerus level. Physical examination shows wristdrop. A photograph is shown. Which of the following transfers is most appropriate to restore wrist extension in this patient?
A ) Axillary to radial nerve transfer
B ) Biceps to triceps muscle transfer
C ) Brachioradialis to extensor carpi ulnaris tendon transfer
D ) Phrenic nerve to posterior cord transfer
E ) Pronator teres to extensor carpi radialis tendon transfer
E ) Pronator teres to extensor carpi radialis tendon transfer
Pronator teres to extensor carpi radialis brevis (ECRB) transfer is well described for restoration of wrist extension in isolated radial nerve injury or palsy. The pronator teres is harvested from its insertion on the radius alongwith an extension of radius periosteum (necessary to have sufficient length for the transfer) and is woven either end-to-end into the ECRB or end-to-side into the ECRB if the surgeon feels the ECRB may recover some function.
Restoration of wrist extension in isolated radial nerve palsy
Pronator teres to extensor carpi radialis brevis (ECRB) transfer is well described for restoration of wrist extension in isolated radial nerve injury or palsy.
Procedure for Pronator teres to extensor carpi radialis brevis transfer?
The pronator teres is harvested from its insertion on the radius alongwith an extension of radius periosteum (necessary to have sufficient length for the transfer) and is woven either end-to-end into the ECRB or end-to-side into the ECRB if the surgeon feels the ECRB may recover some function.
Why is radius periosteum essential for pronator teres to extensor carpi radialis brevis transfer?
Necessary to have sufficient length for the transfer
Innervation of the brachioradialis muscle
Radial nerve
Axillary-radial nerve coaptation
Axillary-radial nerve coaptation is performed in the proximal upper arm and uses the radial nerve as a donor to provide axons to the axillary nerve and deltoid muscle.
A 36-year-old man comes to the office because of weakness in the right hand 4 months after sustaining a saw injury to the volar ulnar aspect of the proximal right forearm. At the time of injury, the wound was cleaned and sutured in the emergency department. Current physical examination shows finger clawing and ineffectual gripping of the right hand. An injury to the ulnar nerve is noted. Which of the following is the most effective transfer to restore function to the intrinsic hand muscles in this patient?
A ) Anterior interosseous nerve branch to the pronator
B ) Extensor carpi radialis longus tendon
C ) Flexor carpi ulnaris fascicle nerve
D ) Flexor digitorum superficialis tendon
E ) Medial antebrachial cutaneous nerve
A ) Anterior interosseous nerve branch to the pronator
The classically described nerve transfer for a high ulnar nerve palsy to restore hand intrinsic motor function is to use the anterior interosseous branch to the pronator quadratus as a transfer into the ulnar motor nerve branch.
Both extensor carpi radialis longus transfer and the Zancolli flexor digitorum superficialis lasso procedure have been described for the ulnar claw posture of the fingers, but the potential advantage of a nerve transfer over a tendon transfer under these circumstances is the capacity for restoration of function of multiple muscle groups with a single nerve transfer.
Oberlin nerve transfer
The Oberlin nerve transfer was described for restoration of elbow flexion in patients with brachial plexus injury. This utilizes the flexor carpi ulnaris fascicle transfer to the musculocutaneous nerve.
Classical nerve transfer for a high ulnar nerve palsy, to restore hand intrinsic motor function
The classically described nerve transfer for a high ulnar nerve palsy to restore hand intrinsic motor function is to use the anterior interosseous branch to the pronator quadratus as a transfer into the ulnar motor nerve branch.
A proximal ulnar nerve lesion with a segmental nerve loss in an adult: potential advantage of a nerve transfer over a tendon transfer
The potential advantage of a nerve transfer over a tendon transfer under these circumstances is the capacity for restoration of function of multiple muscle groups with a single nerve transfer.
A 30-year-old man is referred for poor thumb opposition following an injury to the median nerve at the level of the wrist of the dominant right hand sustained 18 months ago. Physical examination shows strong function of the flexor digitorum superficialis (FDS) and flexor digitorum profundus (FDP) of the little, ring, long, and index fingers. Extension of the wrist, fingers, and thumb is also strong. Which of the following tendon transfers into the abductor pollicis brevis insertion is most appropriate for correction of the deficit in this patient?
A ) Transfer of the extensor carpi radialis brevis
B ) Transfer of the extensor indicis proprius
C ) Transfer of the FDP of the ring finger
D ) Transfer of the flexor carpi ulnaris
E ) Transfer of the flexor palmaris longus
B ) Transfer of the extensor indicis proprius
Transfer of either the FDS of the ring finger or the extensor indicis proprius (EIP) is appropriate.
Transfer of the FDP of the ring finger is inappropriate because distal interphalangeal flexion of the ring finger would be lost.
Transfer of the palmaris longus is often performed during a carpal tunnel release following long-standing median nerve compression to augment weakened thenar muscles, but this tendon transfer does not provide as much opposition strength as the EIP and FDS transfers in lower median nerve palsy. This is especially true for reconstruction of the dominant hand.
Low median nerve palsy
Loss of thumb opposition only
High median nerve palsy
Loss of all FDS function, loss of FDP function of the index and long fingers, loss of flexor palmaris longus function
Tendon transfer options for opponensplasty
Transfer of either the FDS of the ring finger or the extensor indices proprius is appropriate
Procedure for FDS of the ring finger transfer for opponensplasty
FDS transfer requires formation of a pulley at approximately the level of the pisiform. This is most easily created using the ulnar half of the flexor carpi ulnaris tendon
Procedure for EIP transfer for for opponensplasty
The EIP tendon is long and can be easily routed around the ulnar aspect of the forearm and still reach the thumb proximal phalanx, obviating the need for a pulley.
Opponensplasty: Transfer of the EIP versus FDS of the ring finger
EIP is nsidered by many authors to be superior to the FDS transfer because possible adhesion formation to a constructed pulley is avoided.
Using the palmaris longus tendon after carpal tunnel release
Transfer of the palmaris longus is often performed during a carpal tunnel release following long-standing median nerve compression to augment weakened thenar muscles
A 56-year-old man with a 10-year history of pain in the wrist caused by rheumatoid arthritis comes to the office for consultation regarding surgical treatment options. Total joint replacement (arthroplasty) is a more appropriate choice than joint fusion (arthrodesis) if this patient indicates that his primary goal is which of the following? A ) Grip strength B ) Pain relief C ) Proper alignment D ) Range of motion E ) Stability
D ) Range of motion
Fusion provides stability and allows pain-free function. It can restore anatomical alignment, and grip strengthcan be quite good. Arthroplasty also provides pain relief and corrects alignment. Generally speaking, arthroplasty does not provide the stability or strength of arthrodesis. The decision to pursue arthroplasty over arthrodesis is usually made because of the patient’s desire or necessity to preserve as much range of motion as possible.
Choosing between arthroplasty and arthrodesis for a painful joint
Fusion provides stability and allows pain-free function. It can restore anatomical alignment, and grip strengthcan be quite good.
Arthroplasty also provides pain relief and corrects alignment, but does not provide the stability or strength of arthrodesis.
The decision to pursue arthroplasty over arthrodesis is usually made because of the patient’s desire or necessity to preserve as much range of motion as possible.
A 63-year-old man with a five-year history of rheumatoid arthritis comes to the office because he has had recurrent painful triggering of the ring and small fingers of the right hand for the past four months. He has not had numbness or tingling of the fingers. The ring and small fingers trigger and lock. A radiograph is shown. Which of the following is the most appropriate management?
A ) A1 pulley release
B ) Centralization of extensor mechanism and repair of the sagittal bands
C ) Replacement of the metacarpophalangeal (MCP) joint
D ) Tenolysis of superficialis and profundus tendons
E ) Tenosynovectomy and resection of slip of the superficialis tendon
E ) Tenosynovectomy and resection of slip of the superficialis tendon
In patients with rheumatoid arthritis, the A1 pulley should be preserved and a flexor tenosynovectomy of the fingers should be performed as well as, if necessary, a resection of one slip of the superficialis tendon.
A 65-year-old woman with long-standing rheumatoid arthritis comes to the office because she has been unable to extend the thumb and fingers of her nondominant left hand for the past eight weeks. Examination shows moderate rheumatoid arthritis with caput-ulnae syndrome, zigzag deformity of the left hand, and a boggy fullness over the extensor tendons at the wrist and around the elbow. Testing for tenodesis effect shows extension of the digits on passive flexion of the wrist. Which of the following is the most likely cause of the disability in this patient?
A ) Attritional rupture of the extensor tendons
B ) Compression of the posterior interosseous nerve
C ) Contracture of the ulnar-sided collateral ligaments of the metacarpophalangeal (MCP) joints
D ) Subluxation of the extensor tendons into the gutter between the MCP joints
E ) Tightness of the intrinsic lumbrical muscles
B ) Compression of the posterior interosseous nerve
Posterior interosseous nerve (PIN) compression is a complication of rheumatoid arthritis which, together with extensor tendon rupture and metacarpophalangeal joint dislocation, should be considered in the differential diagnosis of inability to extend the fingers.
The inability to extend the thumb in PIN entrapment can be a useful distinguishing clue on physical examination.
Differential in a patient with posterior interosseous syndrome who is unable to extend the fingers
Posterior interosseous nerve (PIN) compression, extensor tendon rupture and metacarpophalangeal joint dislocation, should be considered in the differential diagnosis of inability to extend the fingers in a patient with rheumatoid arthritis
Differentiating posterior interosseous syndrome from other causes of inability to extend the fingers in a patient with rheumatoid arthritis
The inability to extend the thumb in PIN entrapment can be a useful distinguishing clue on physical examination.
Cause of posterior interosseous syndrome in patients with rheumatoid arthritis
Elbow joint swelling and compression of the PIN at the arcade of Frohse are the main reasons for PIN entrapment in rheumatoid arthritis.
Treatment for symptoms of posterior interosseous syndrome in patients with rheumatoid arthritis
Elbow joint swelling and compression of the PIN at the arcade of Frohse are the main reasons for PIN entrapment in rheumatoid arthritis.
Intraarticular corticosteroid injections and surgical intervention resolve symptoms of PIN entrapment in rheumatoid arthritis.
Caput-ulnae syndrome
Caput-ulnae syndrome is a dorsal dislocation of the distal ulna resulting from synovitis, ligament laxity, and extensor carpi ulnaris tendon translocation. Erosions in the prominent ulna put the extensor tendons at risk of attritional rupture.
A 35-year-old woman comes to the office for consultation because she has had rapidly progressive contractures of the thumb and index fingers of both hands and development of knuckle pads during the past nine months. She also has 1.5-cm painful nodules on the soles of both feet. Which of the following is the most likely cause of the patient’s disease?
A ) Decrease in apoptotic gene expression
B ) Decrease in ratio of type III to type I collagen
C ) Deposition of antigen-antibody complexes
D ) Inheritance of an autosomal recessive trait
E ) Proliferation of myofibroblasts
E ) Proliferation of myofibroblasts
The most likely causative event in the scenario described is proliferation of myofibroblasts. The patient described presents with Dupuytren diathesis, a phenomenon of rapidly progressing contractures in a young person.
Phases of Dupuytren disease
The three pathophysiologic phases of Dupuytren disease are the proliferative, involutional, and residual stages.
Proliferative stage of Dupuytren disease
he proliferative stage is characterized by an intense proliferation of myofibroblasts.
Involutional stage of Dupuytren disease
The involutional stage is characterized by the alignment of the myofibroblasts along lines of tension.
Residual stage of Dupuytren disease
During the residual stage, the tissue becomes mostly acellular and devoid of myofibroblasts, and only thick bands of collagen remain.
Dupuytren diathesis and patient gender
There does not seem to be a correlation between Dupuytren diathesis and patient gender.
Dupuytren diathesis
A diathesis can be recognized when there is a strong family history in a patient who is young at the time of onset and presents with bilateral disease, especially with radial-sided disease or diffuse dermal involvement.
Dupuytren disease and ectopic manifestation
Ectopic deposits have been described on the soles of the feet (Lederhose disease), over the dorsum of the proximal interphalangeal joints (Garrod knuckle pads), and on the penis (Peyronie disease)
Peyronie disease
Dupuytren disease on the penis