Hand 1 Flashcards
Order from inner to outer
Myelin
Perineurium
Endoneurium
Fascicles
Epineurium
Axon
Axon
Myelin
Endoneurium around individual axons
Fascicle = group of axons
Perineurium around fascicle
Epineurium around group of fascicles
What cells make myelin
Schwann cells
What is the intrinsic vs extrinsic BS to nerves
Intrinsic: plexus within loose connective tissue / epineurium
Extrinsic : vasa nervosum
How do APs move between areas of myelin? What are these areas called?
Nodes of Ranvier
Saltatory conduction here
How care for the following nerve injuries:
Laceration
Open wound w/ nerve rupture
Closed injuries
Laceration = fix ASAP to avoid fibrosis/retraction
Open wound w/ nerve rupture = allow demarcation (2-3wks) so you can resect all dead tissue for a healthy wound bed at time of repair
Closed injuries = watch 3-6mo recovery
Define following terms and recovery time
Neurapraxia
Axonotmesis
Neurotmesis
Neurapraxia - axonal level nerve block
Conduction block, architecture preserved
<3mo
Axonotmesis - discontinuity of axons
Surrounding nerve tube acts as a guide to allow nerve to grow in the right direction
1mm/day
Neurotmesis - complete disruption of entire nerve
Requires surgical intervention
What are the EMG findings for the following
Neurapraxia
Axonotmesis
Neurotmesis
Neurapraxia
- Normal insertional activity
- No spont activity
Axonotmesis and neurotmesis hard to differentiate on EMG
- Increased insertional activity
- Fib/positive sharp waves spont activity
What are the best options for nerve repair in the given circumstances:
No tension
<2-3cm gap in sensory nerve
<5cm defect
>5cm defect
No tension - direct repair!
= epineurium repair (not fascicle repair bc more scarring)
- Max 10% stretch
<2-3cm gap in sensory nerve - conduit
GRAFT
<5cm defect - allograft but only for sensory n
>5cm defect or any motor involvement - autograft
What are your options for a digital nerve defect?
SENSORY only!!!
Primary repair
<3cm = conduit
>3cm = allograft of autograft
Autograft of choice is MABC > LABC
What is the double Oberlin transfer? What is it done for?
Gain elbow flexion (feeding goal)
Ulnar n from FCU
Median n from FDS/FCR
To motor br biceps/brachialis
What does EMG vs NCS measure?
EMG: electrical activity of muscle w/ voluntary contraction
NCS: nerve conduction velocity, latency, amplitude
NCS
- What happens w/ axonal loss
- What happens w/ demyelination
Axonal loss: drop amplitude
- Still conducting, just not as strong
Demyelination: drop velocity -> increase latency
What is most common cause of CTS
Edema / vascular sclerosis
Reduced epineurial blood flow
Splinting keeps pressure at neutral to keep blood flow constant
In theory a CSI should work for CTS bc not inflammatory
What are the 2 ways to test sensory nerves? Examples of each
Threshold test = measures 1 nerve fiber innervating a receptor. Best for eval nerve after repair
- Static vs moving 2 pt discrimination
Innervation density test = multiple overlapping receptive fields. Best for gradual nerve changes (compressive neuropathy)
- Semmes Weinstein monofilament
- Vibration tests
What are the best provocative tests for CTS
Direct compression > Phalen > Tinel
Semmes Weinstein (density test) > 2 pt discrim (threshold)
Findings on EMG for CTS
Distal motor latencies > 4.5 msec
Sensory latencies > 3.5 msec
Benefit of endoscopic > open CTR
Endoscopic = open long term
Quicker return to work (less incisional/pillar pain early)
Cons: $$, higher risk complication
4 sites of median nerve compression (not CTS)
Ligament of struthers = supracondylar process humerus (get an XR)
Lacertus fibrosis (aka biceps aponeurosis)
Deep head pronator (medial epicondyle/deep volar forearm) - why pronator syndrome often associated with medial epicondylitis
FDS arcade
How do you determine a proximal compressive median neuropathy vs CTS
Proximal compression you’ll have the sensory br median nerve involved (palm numbness)
AIN syndrome
- Sx
- Muscles innervated
- Causes
- Trt
Sx: forearm pain, inability to make O sign index/thumb
Different than other median compressive neuropathy bc motor involvement
- FPL
- FDP index/long
- PQ
Causes:
- Compression by FDS/FCR/PT/FPL
- Parsonage Turner (viral)
- Ddx = tendon rupture (think RA)
Trt: obs obs obs obs