HAEMORRHAGE Flashcards
Define antepartum haemorrhage
Bleeding from or into genital tract from 24 weeks gestation (viability) and prior to birth of baby (until first and second stage labour)
Name 4 main causes antepartum haemorrhage
- Abruptio placenta
- placenta praevia / vasa praevia
- local causes: lacerations, infection (cervicitis,vaginitis), cancer, trauma, warts, ulcers…
- APH of unknown origin
( Uterine rupture )
Name 8 risk factors antepartum haemorrhage caused by abruptio placenta
Placental factors
- previous abruption
Maternal factors
- pre-eclampsia !, hypertensive disease in pregnancy
- SLE , APLS (antiphospholipid syndrome)
- AMA
- Poor social economic status, multiparity
- smoking and drug use (cocaine)
Uterine /pregnancy factors
- fetal growth restriction: polyhydramnios
- prom
-, multiple gestation - intra-uterine infection
Mechanical
- abdominal trauma
Name 8 causes / risk factors antepartum haemorrhage caused by placenta praevia
Placental factors
- Previous placenta praevia
- Placentomegaly, abnormal formation of placenta
Endometrial factors
- previous C section
- previous top
- congenital uterine abnormalities
- Deficient endometrium eg uterine scar, Endometritis , curettage, myomectomy
- multiple pregnancy
Lifestyle
- smoking
- AMA
Conceptus related factors
- assisted conception
- delay in development/ maturation of fertilised ovum
Cause of tense/ woody uterus?
Significant abruption
When should digital examination be avoided?
Placenta praevia
Premature rupture of membranes
Management antepartum haemorrhage? (9)
- Determine if shocked and resuscitate
- admit if APH heavier than spotting, and ongoing bleeding, until stopped. If placenta praevia and bled, hospitalise until delivery
- history for risk factors
- examination : no pv until exclude praevia!
- investigations: blood, ultrasound
- check baby: ga, ctg
/ - manage according to cause
- corticosteroids 26 -34 weeks if risk preterm
- tocolysis only if mom and baby stable
- if foetal death→ vaginal delivery with active manage 3rd stage labour
- foetal compromise → c/s immediately
- if unexplained APH and no maternal/foetal compromise, plan delivery at 37 weeks
- continuous ctg if active bleeding, early pregnancy major APH, recurrent minor APH, clinical abruption, evidence placental insufficiency
- anti D ig to all non sensitised Rh negative independent of whether routine prophylaxis has been given. If recurrent bleeding after 20 weeks, give anti-d at 6 weekly intervals
Define primary postpartum haemorrhage
First 24 hours after delivery
Blood loss > 500 ml after vaginal, 1000 ml after c/S
Define secondary postpartum haemorrhage
24 hours - 6 weeks after delivery
> 500 ml vaginal, 1000 c/s
Define persistent postpartum haemorrhage
Active bleedin > 1000 ml within 24 hours following birth that continues despite use initial measures including uterotonics and massage
Prevention postpartum haemorrhage (6)
- Active management 3rd stage labour:
→ uterotonic
> uncomplicated vaginal: syntocinon 5 or 10 iu IM
> C section: syntometrine (oxytocin/ ergometrine) 2,5 iu by slow iv injection
> CVS disorders: low dose infusion oxytocin safer than bonus
→ early clamping umbilical cord
→ controlled traction for placental delivery for potential risk PPH - all with previous c/s, determine placental site un ultrasound. Prepare for resuscitation if any abnormalities diagnosed
- iron supplements antenatally if iron deficiency anaemia
Name 5 causes postpartum haemorrhage
4 Ts
- tone: uterine atony
- Trauma to genital tract
- thrombosis: coagulation defects
- tissue: retained products of conception
- uterine inversion
Stepwise Medical treatment uterine atony? (7)
- Bimanual uterine compression
- Ensure empty bladder -catheter
- syntocinon (oxytocin/ergometrine) 5 iu by slow iv injection (may be repeated)
- ergometrine 0,5 mg slow iv (contraindicated in ht)
- syntocinon infusion 30 iu in 1L ringer’s
- tranexamic acid 500 - 1500 mg iv
- misoprostol 1000 ug rectally
Approach to postpartum haemorrhage after vaginal delivery? (10)
Resuscitate
→ rub up uterus/ bimanual compression
→ call for help
→ 2 large bore iv
→ infusion oxytocin 20 U in 1 L ringers
→ maintain bp with clear fluids/blood
→ catheter
→ monitor bp/pulse/urine output
Check placenta
- undelivered: repeat cord traction and manually remove
- incomplete: evacuate uterus, digital exploration , ovum forceps and largest curette
If complete /ongoing bleed, check uterus
- soft
→ massage uterus and expel clots
→ continue oxytocin infusion
→ ergometrine 0,5 mg or syntometrine 1 amp IM (repeat once if, needed)
→ misoprostal 400 - 600 ug Pr or sublingual
→ tranexamic and 1 G iv ( can repeat x 1) - Firm: suture lacerations perineum, vagina, cervix
- not felt: check vaginally for inverted uterus
→ replace immediately
→ hydrostatic reduction: saline infusion into vagina. Hold vulvae around tube or use rubber vacuum cup in vagina forseal
If ongoing bleedin
- tranexamic acid 1 g iv
- examine in theatre , while wait place anti shock garment and balloon tamponade to reduce bleed,
- explore for retained products and deep lacerations
- laparotomy:
→ aortic compression
→ uterine compression sutures ( b lynch)
→ uterine artery ligation
→ hysterectomy
Management PPH after vaginal delivery + resus, with soft uterus? (5)
→ massage uterus and expel clots
→ continue oxytocin infusion
→ ergometrine 0,5 mg or syntometrine 1 amp IM (repeat once if, needed)
→ misoprostal 400 - 600 ug Pr or sublingual
→ tranexamic and 1 G iv ( can repeat x 1)
Management ongoing PPH after vaginal delivery , when resuscitation has been performed and placenta and uterus examined and managed? (7)
- tranexamic acid 1 g iv
- examine in theatre , while wait place anti shock garment and balloon tamponade to reduce bleed,
- explore for retained products and deep lacerations
- laparotomy:
→ aortic compression
→ uterine compression sutures ( b lynch)
→ uterine artery ligation
→ hysterectomy
Approach to management post partum haemorrhage after ceserean section (6)
- Call for more senior help
- resuscitates / early treatment by anaesthetist
- arrest haemorrhage (surgeon) (proceed immediately to subtotal hysterectomy irreparable uterine rupture or placenta percreta )
Determine cause
- atonic uterus:
- tears:
- Placental site bleeding:
Classify perineal tears (6)
- First degree: injury to perineal skin only
- second: involve perineal muscles but not anal sphincter
- third: involve anal sphincter complex
→ 3a: < 50% of external anal sphincter thickness torn
→ 3b: > 50%
→ 3c: both external and internal anal sphincter torn - fourth: involve anal sphincter complex (internal and external) and anal epithelium
Define buttonhole tear. Complication?
Involve only anal mucosa with intact anal sphincter complex, must be documented as separate entity to perineal tear.
Can → anovaginal fistula
How repair first and second degree perineal tear?
Bedside sutures
How repair third and fourth degree perineal tear? (3)
In theatre.
External anal sphincter: overlapping or end to end (approximation) method with monofilament sutures ( eg PDS polydiaxanone ) or modern braided sutures (vicryl polyglactin)
Internal: interrupted fine sutures with 3-0 PDS or 2-0 vicryl