Haemophilus

Question 1

caractere morfofunctionale

Answer 1

bacili gram -
imobili
capsulati => tulpinile virulente

Question 2

caract de cultura

Answer 2

depend de prezenta in mediul de cultura a 2 fact de crestere :
fac X = hemina
fac V = nicotinamide adenin dinucleotid (NAD)
cultiva pe geloza chocolat
colonii:
-plate
-transparente
-nepigmentate
cultiva pe geloza sange de berbec in vecinatate cu S. aureus

Question 3

caractere metabolice

Answer 3

aerob facultativ anaerob
catalazo +
oxidazo +
descomplune fermentativ glucoza
trei caract biochimice :
-ureaza +
-indol +
-ornitin decarbozilaza +

Question 4

factori de virulenta

Answer 4

capsula
fimbii sau pili
proteine
LOS

Question 5

capsula

Answer 5

de natura polizaharidica
clasificare in 6 serotipuri
contine riboza si ribitol fosfat
confera prop antifagocitare si rezistenta la efectul litic al complementului

Question 6

cate tiprui de protine sunt

Answer 6

majore => adezine

de legare a transferinei => de obt a Fe

Question 7

patogeneza

Answer 7

H influzae => meningita la copii

H ducrey => sacrul moale la om

Question 8

habitat

Answer 8

omul => singura gazda naturala

tulpinile necapsulate => colonizeaza frecvent mucoasa oro-faringiana si nazo-farigiana

Question 9

in ce prod patologice

Answer 9

sputa
LCR
exsudate nazofaringiene 
exsudate vaginale 
puroi

Question 10

microscopie

Answer 10

coloratie gram
gram -
colonii plate, rotunjite, mici
transparente

Question 11

detectare antigenica

Answer 11

latex aglutinare => Ag polizaharidic capsular PRP

reactia de umflare => ser anti-H. influzae

Question 12

izolare

Answer 12

geloza sange
geloza chocolat
bulion hemoglobinat
mediul Fildes
geloza Levinthal

Question 13

ce fact de crestere necesita

Answer 13

fac V si fac X

Question 14

caract de cultura

Answer 14

geloza chocolat - colonii mici, rotunde, transparente

geloza sange - in paralel cu S. aureus

Question 15

identificare biochimica

Answer 15

ureaza +

indol +

Question 16

tratament

Answer 16

cefalosporine 
aminopeniciline
carbapeneme 
fluorochinolone
cloramfenicol
rifampicina
tetracicline