Campylobacter Flashcards

1
Q

care sunt cele 2 fam din ordinul Campylobacter

A

Campylobacter si Helicobacter

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2
Q

care sunt caracteristicile

A
bacili Gram -
forma spiralata
nesporulati 
crestere microaerofila 
nu fermenteaza si nu oxideaza glucoza => greu de izolat
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3
Q

generalitati Campylobacter

A

bacili Gram -
forma spiralata
mobili cu flageli spolari
nesporulati

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4
Q

care sunt speciile de Campylobacter

A

C. jejuni

C. fetus

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5
Q

cum se face transmiterea

A

de la animale

suprafete si ape contaminate

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6
Q

cand este crescuta incidenta

A

vara

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7
Q

ce factor de virulenta prezinta

A

LOS in loc LPZ

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8
Q

ce prezinta C. jejuni

A

adezine
enterotoxine
enzime citotoxice
rolul lor nu este clar in patogenitate

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9
Q

cum actioneaza C. jejuni

A

penetreaza mucoasa => se ataseaza de enterocite => patrunde intracelular => invazie in veziculele delimitate de endomembrana

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10
Q

care este raspunsul gazdei dupa invazia C. jejuni

A

raspuns inflamator => IL-8 => cheama celulele inflamatorii

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11
Q

ce favorizeaza boala

A

scaderea aciditatii sucului gastric

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12
Q

enterocolita acuta

A

95% C. jejuni
5% C. coli
afecteaza in principal nou-nascutii si copii
diaree apoasa urat mirositoare cu 10 sau mai multe scaune/zi
aparitia sangelui in scaun, febra, dureri abdominale
autolimitata 7 zile
aspectul mucoasei :
leziuni ale mucoasei jejunului, ileonului si colonului => mucoasa ulcerata, edematoase si sangeranda
abcese in glandele mucoasei
lamina propria este infiltrata cu PMN, celule mononucleare si eozinofile

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13
Q

sindromul Guillain-Barre

A

= neuropatie periferica inflamatorie demielinizanta autoimuna
asociata cu O:19
asemanarea : intre oligozaharidele unor tulipici de C. jejuni si gangliozidele de la niv nervilor periferici

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14
Q

artrita reactiva

A

inflamatie dureroasa a articulatiilor, gleznei si genunchiului
complicatie tardiva cu Campylobacter

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15
Q

cum se face examinarea microscopica

A

prin caract morfologice
bacili gram -
forma spiralata

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16
Q

in ce atm se cultiveaza

A

microaerofila

17
Q

care sunt caract biochimice

A

oxidaza +

catalaza +

18
Q

tratament

A

tratament enterite => eritromicina fie cu tetraciline fie cu fluorochinolone
tratament infectii sistemice => aminoglicozide cu imipenem