Haematuria Flashcards

1
Q

causes of false haematuria

A
  • Beetroot
  • Rifampicin
  • Porphyria
  • Vaginal bleeding
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2
Q

rare causes of haematuria

A
  • Henoch-Schonlein purpura

- bleeding diathesis

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3
Q

renal causes of haematuria

A
  • Infarct
  • Trauma: inc. stones
  • Infection
  • Neoplasm
  • GN
  • Polycystic kidneys
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4
Q

ureter causes of haematuria

A
  • stone

- tumour

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5
Q

bladder causes of haematuria

A
  • Infection
  • Stones
  • Tumour
  • Exercise
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6
Q

prostate causes of haematuria

A
  • BPH
  • Prostatitis
  • tumour
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7
Q

urethra causes of haematuria

A
  • Infection
  • Stones
  • Trauma
  • Tumour
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8
Q

specific questions to ask in a haematuria history

A
  1. Timing?
    - Beginning of stream: urethral
    - Throughout stream: renal / systemic, bladder
    - End of stream: bladder stone, schisto
  2. Painful or painless?
  3. Obstructive symptoms?
  4. Systemic symptoms: wt. loss, appetite
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9
Q

investigations for haematuria

A
  1. Bloods: FBC, U+E, clotting
  2. Urine: dip, MC+S, cytology
  3. Imaging
    - Renal US
    - IVU
    - Flexible cystoscopy + biopsy
    - CT/MRI
    - Renal angio
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10
Q

causes of asymptomatic haematuria

A
  1. IgA Nephropathy/Berger’s disease
  2. Thin Basement Membrane Disease
  3. Alport’s syndrome
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11
Q

features of IgA nephropathy/Berger’s disease

A
  • most common form of glomerulonephritis
  • Young male with episodic macroscopic haematuria
    occurring a few days after Upper Respiratory Tract Infection.
  • Rapid recovery between attacks
  • ↑IgA
  • Can occasionally → nephritic syndrome
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12
Q

biopsy results of IgA nephropathy/Berger’s disease

A

IgA deposition in mesangium

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13
Q

treatment of IgA nephropathy/Berger’s disease

A

steroids or cyclophosphamide if ↓renal function

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14
Q

prognosis of IgA nephropathy/Berger’s disease

A

20% End stage renal disease after 20yrs

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15
Q

features of thin basement membrane disease

A
  • Autosomal dominant
  • Commonest cause of asymptomatic haematuria
  • Persistent, asymptomatic microscopic haematuria
  • V. small risk of END Stage renal disease
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16
Q

features of Alport’s syndrome

A
  • 85% X-linked inheritance
  • Haematuria, proteinuria → progressive renal failure
  • Sensorineural deafness
  • Lens dislocation and cataracts
  • Retinal “flecks”
  • Females: haematuria only