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Pharmacology > Haematinics > Flashcards

Haematinics Flashcards

1
Q

Fibrinolytic or thrombolytic drugs

A 
Streptokinase
Urokinase
Alteplase (rt- tpa)
Reteplase
Tenecteplase
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2
Q

Antifibrinolytic/antithrombolytic drugs

A

Amino-caproic acid

Tranexamic acid

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3
Q

Uses of fibrinolytics

A 
MI
Deep vein thrombosis
Pulmonary embolism
Limb perfusion
Decrease infarct size
Improve right ventricular function
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4
Q

Contraindications to fibrinolytics

A 
Diabetic patients
Liver damage
Peptic ulcer
Hypertension
Stroke trauma
Surgery
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5
Q

Uses of antifibrinolytics

A 
Tooth extraction
Prostate surgery
Haemophilia
Tonsillectomy
Menorrhagia
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6
Q

Dipyridamole is used in postoperative prosthetic heart valve condition with

A

Warfarin

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7
Q

Which is better in prasugrel clopidogrel and ticlopidine

A

Prasugrel
Faster
Better

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8
Q

ADR of ticlopidine

A

Neutropenia

Thromcytopenic purpura

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9
Q

Some Gp2a/3b receptor blockers used are

A 
Abciximab
Tirofiban
Eptifibatide
Percutaneous coronary intervention
Angina
MI
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10
Q

Iron preparations

A

Ferrous sulphate

Ferrous fumarate

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11
Q

For iron poisoning

A

desferroxamine

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12
Q

Heparin toxicity can be treated with

A

Protamine sulfate

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13
Q

Drugs incresing anticoagulant activity

A

Aspirin
Ibuprofen
Warfarin

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14
Q

Decreased antcoagulant effects with

A

Digitalis
Tetracycline
Antihistamin
Nicotine

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15
Q

Warfarin act on

A

Factor 2,7,9,10

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16
Q

Geparin acts on

A

Antibrombin 3

17
Q

Warfarin inhibit vit k by blocking

A

Vit k epoxide reductase(VKOR)

18
Q

First coagulant factor to run out

A

Factor 7

19
Q

Warfarin INR

A

2-3

20
Q

Increase warfarin metabolism

A

Barbiturates
Phenytoin
Carbamazepine

21
Q

Decrease warfarin metabolism

A

Cimetidine
Omeprazol
Metronidazole
Cotrinoxazole

22
Q

Protein c deficiency adverses

A

Warfarin induced skin necrosis

23
Q

Prolonged thrombin time

A

Direct thrombin inhibitors

24
Q

Prolonged PT and aPTT

A

Direct factor 10 inhibitors

Pharmacology (16 decks)

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