Git

Question 1

Moa of loperamide(antidiarrhoel)

Answer 1

Stimulation of mu and delta receptors causing decreased paristalsis

Question 2

ADR of diphenoxylate

Answer 2

Anti diarrhoel

Hepatic coma
Atropine related

Question 3

Loperamide is contraindicated in

Answer 3

Children <4

Qt prolongation

Question 4

WHO-ORS composition

Answer 4

Kcl     -1.5 g
Nacl.  - 2.6 g
Na citrate.  - 2.9g
Glucose.     - 13.5g
Water.    -1L

Question 5

Total osmolarity of ORS

Answer 5

245mOsm/L

Question 6

Drug used in diabetes+ autonomic neuropathy + diarrhoea

Answer 6

Clonidine

ADR
Depression
Hypotension

Question 7

Racecadotril is an

Answer 7

Antidiarrhoeal
Prodrug
Enkephalinase inhibitor
Decreases intestinal sectetions

Question 8

ADR of sulphasalazine

Answer 8

Fever
Hepatitis
Pancreatitis
Pneumonitis

Question 9

lactulose is used for the tt of

Answer 9

Hepatic encephalopathy

Question 10

Docusates should not be given with liquid paraffin as

Answer 10

They increase paraffin absoption

Question 11

Anthraquinine derivatives should not be given to lactating mothers as

Answer 11

Derivatives such as Senna is secreated in milk

Question 12

Categories of Laxatives used are

Answer 12

Bulk forming (bran,polycarbophil)
Stool softeners(docusate,paraffin)
Stimulants (bisacodyl,senna)
Osmotic(mg,na salts)

Question 13

Melanosis coli is seen in

Answer 13

Senna (anthraquinone derivative)

Laxatives

Question 14

Functional constipation

Answer 14

Bulk laxatives

Question 15

Prevent straining,hernia

Answer 15

Docusate

Bulk laxatives

Question 16

Lactulose especially for

Answer 16

Hepatic coma

Question 17

Laxatives used in Bowel Surgery, colonoscopy,x-ray are

Answer 17

Osmotic laxatives

Bisacodyl

Question 18

Drug poisoning tt

Answer 18

Saline laxatives(Mg sulphate)

Question 19

Tt constipation in children and pregnant

Answer 19

Lactulose