HAART Flashcards
NRTI mechanism
Inhibit production of viral DNA from RNA
NRTIs (nucleoside)
Abacavir
Emtricitabine
Lamivudine
NRTIs (nucleotide)
Zidovudine
Tenofovir
NRTI AEs
Lactic acidosis (can be fatal) Lipodystrophy
NNRTI mechanism
Inhibit production of viral DNA from RNA
NNRTIs
Efavirenz
Etravirine
Rilpirvirine
NNRTI AEs
Rash
Protease inhibitor mechanism
Interfere w/ viral replication and cause production of nonfunctional viruses
Protease inhibitors
-navir Atazanavir Darunavir Fosamprenavir Lopinavir Ritonavir
Integrase inhibitor mechanism
Blocks integration of viral genome into host genome
Integrase inhibitors
-gravir
Elvitegravir
Raltegravir
CCR5 antagonist
Prevents viral entry by blocking CCR5 coreceptor
Maraviroc
Fusion inhibitor
Binds glycoprotein 41 blocking HIV virus fusion to CD4 cells
Envuvirtide
Antiretroviral w/ possibly fatal hypersensitivity rxn
Abacavir (NRTI)
Antiretroviral w/ BM suppression, anemia
Zidovudine (NRTI)