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Medications > HAART > Flashcards

HAART Flashcards

1
Q

NRTI mechanism

A

Inhibit production of viral DNA from RNA

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2
Q

NRTIs (nucleoside)

A

Abacavir
Emtricitabine
Lamivudine

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3
Q

NRTIs (nucleotide)

A

Zidovudine

Tenofovir

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4
Q

NRTI AEs

A 
Lactic acidosis (can be fatal)
Lipodystrophy
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5
Q

NNRTI mechanism

A

Inhibit production of viral DNA from RNA

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6
Q

NNRTIs

A

Efavirenz
Etravirine
Rilpirvirine

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7
Q

NNRTI AEs

A

Rash

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8
Q

Protease inhibitor mechanism

A

Interfere w/ viral replication and cause production of nonfunctional viruses

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9
Q

Protease inhibitors

A 
-navir
Atazanavir
Darunavir
Fosamprenavir
Lopinavir
Ritonavir
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10
Q

Integrase inhibitor mechanism

A

Blocks integration of viral genome into host genome

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11
Q

Integrase inhibitors

A

-gravir
Elvitegravir
Raltegravir

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12
Q

CCR5 antagonist

A

Prevents viral entry by blocking CCR5 coreceptor

Maraviroc

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13
Q

Fusion inhibitor

A

Binds glycoprotein 41 blocking HIV virus fusion to CD4 cells

Envuvirtide

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14
Q

Antiretroviral w/ possibly fatal hypersensitivity rxn

A

Abacavir (NRTI)

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15
Q

Antiretroviral w/ BM suppression, anemia

A

Zidovudine (NRTI)

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16
Q

Antiretroviral w/ depression, vivid nightmares, teratogen

A

Efavirenz (NNRTI)

17
Q

Antiretroviral w/ hyperbilirubinemia, jaundice

A

Atazanavir

18
Q

Protease inhibitor AEs

A

Hyperglycemia, DM, +TG

GI toxicity

19
Q

Antiretroviral that inhibits P450, “boosts” other drugs

A

Ritonavir boosts other protease inhibitors

20
Q

Abacavir

A

NRTI

AE: Possibly fatal hypersensitivity rxn

21
Q

Efavirenz

A

NNRTI

AE: teratogenic; depression, vivid nightmares

22
Q

Atazanavir

A

Protease inhibitor

AE: hyperbilirubinemia, jaundice

23
Q

Emtricitabine

24
Q

Elvitegravir

A

Integrase inhibitor

25
Q

Etravirine

26
Q

Darunavir

A

Protease inhibitor

27
Q

Enfuvirtide

A

Fusion inhibitor

28
Q

Fosamprenavir

A

Protease inhibitor

29
Q

Lamivudine

30
Q

Rilpirvirine

31
Q

Raltegravir

A

Integrase inhibitor

32
Q

Tenofovir

33
Q

Maraviroc

A

CCR5 antagonist

34
Q

Zidovudine

A

NRTI

AE: BM suppression, anemia

35
Q

Lopinavir

A

Protease inhibitor

36
Q

Ritonavir

A

Protease inhibitor (booster)

Medications (10 decks)

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