Gynecological Emergencies/First Trimester Bleeding Flashcards

1
Q

Nonpregnancy related causes of first trimester bleeding

A

polyps, vaginal trauma/laceration, STI

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2
Q

number one ddx on first trimester bleeding

A

ectopic pregnancy! then spontaneous abortion, implantation bleed, ot GTN

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3
Q

risk factors for sponatenous abortion

A
  • age
  • previous miscarriage
  • chronic conditions
  • uterine or cervical problems
  • smoking, alcohol and illicit drugs
  • weight
  • invasice prenatal tests
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4
Q

How does the cervix differ in a threatened vs incomplete spontaneous abortion?

A

threatened: cervix still closed.

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5
Q

Always rule out ___ ___ on PE when evaluating a first trimester bleed

A

acute abdoment

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6
Q

Role of beta HCG during investigations of first trimester bleeding

A

Role of Beta HCG: increases 2x every 48-96 hours in a viable pregnancy. Quantitative value correlates with gestational age and ultrasound findings.

If BHCG>2000 → should see a viable pregnancy on transvaginal U/S.

If serum BHCG <2000 and U/S inconclusive:

  • falling bHCG= non-viable or ectopiv

doubling BHCG= viable OR ectopic (dependent on US)
- plateau or slow rising = ectopic.

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7
Q

role of ultrasound during investigations of first trimester bleeding

A

Role of Transvaginal Ultrasound

Determines if: intrauterine to extrauterine pregnancy, viability, dating, adnexal masses.

If beta HCG >2000, and no intrauterine pregnancy → ectopic pregnancy.

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8
Q

Maagement of spontaneous abortion (expectant and surgical and medical management)

A

Expectant management: follow closely if stable, assume complete if tissue passed and no further bleeding or cramping. There is no role for repeat U/S unless increased symptoms.

Dilation and Curettage: in OR with IV sedation. Risk of infection, bleeding and perforation

Medical Management; misoprostol, dose via pill → 70-90% expulsion rate.

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9
Q

WHen can you assume complete passage of a sponatenous abortion?

A

assume complete if tissue passed and no further bleeding or cramping. There is no role for repeat U/S unless increased symptoms.

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10
Q

Ectopic Pregnancy Definition: pregnancy implanted outside of uterine cavity→ 95% occur in __ __ (85% in __ portion), 1% is ovarian.

A

Definition: pregnancy implanted outside of uterine cavity→ 95% occur in fallopian tube (85% in ampullary portion), 1% is ovarian.

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11
Q

Factors that aid in the diagnosis of an ectopic pregnancy (6)

A
  • nothing in uterus on US
  • high beta HCG
  • pain+++/shock/hemorrage/acute abdomen
  • cystic adnexal mass

- fetal heart rate outside of uterine cavity

- fluid in cul de sac

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12
Q

risk factors for ectopic pregnancy

A

Previous ectopic pregnancy.

Prior fallopian tube surgery.

Previous pelvic or abdominal surgery.

Certain sexually transmitted infections (STIs)

Pelvic inflammatory disease.

Endometriosis.

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13
Q

treatment of ectopic pregnancy

A

methotrexate or surgical: salpingostomy, laparoscopic appraoch

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14
Q

criteria to use methotrexate as a method of management of ectopic pregnancy

A

Treatment: methotrexate, avoid folic acid.

Must be hemodynamically stable, no renal/hepatic disease, small ectopic pregnancy, no fetal HR, bHCG<5000, pt must be able to have follow up

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15
Q

GTN definition

A

Definition: spectrum of disease processes arising from the placenta (abnormal trophoblastic proliferation)

Symptoms: 1st trimester vaginal bleeding, hyperemesis ( high ­BhCG)

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16
Q

differentiate between a complete and incomplete mole of gestational trophoblasic neoplasia

A

• Complete mole: 46XX (2 sperm, empty egg). No fetal
tissue or fetal blood cells presents because the egg has no contents

o Investigations: ­BHCG, snowstorm on US,
commonly ovarian theca lutein cysts

o Complications: malignant in 20%

• Partial mole: tripoidy (normal egg, 2 sperm), consists of
both placenta + fetal parts. Higher b-HCG

o Complication: malignant 5%

17
Q

management of both partial and complete moles of GTN

A

• Benign partial or complete mole: suction curettage, weekly BHCG until normal for 3wk + monthly
titres for 6mo, contraception for 6mo

• Malignant GTN: investigation for mets, methotrexate