Gynecologic Directed Reading Quiz

Question 1

______ is best used to treat well-delineated, small volume tumors situated close to radiation sensitive healthy tissues.

Answer 1

brachytherapy

Question 2

Endometrial cancer recurrence in vaginal tissues can be treated with salvage ______ plus 3-D image-guided brachytherapy.

Answer 2

IMRT

Question 3

The molecular genetics and histology of gynecologic cancers can vary significantly.

Answer 3

True

Question 4

Bragg peak describes the dose distribution of:

Answer 4

proton therapy

Question 5

The uterine walls contain which of the following tissue layers?

1. endometrium
2. myometrium
3. perimetrium

Answer 5

1, 2, and 3

Question 6

The International Federation of Gynecology and Obstetrics (FIGO) staging system does not yet formally include imaging examinations in staging gynecologic cancers.

Answer 6

True

Question 7

Presence of elevated levels of the biomarker CA125 is:

Answer 7

not unique to changes in ovarian tissues, and not
always reliable as a screening tool.

Question 8

The Risk of Malignancy Index can differentiate benign from malignant ovarian masses in postmenopausal women by combining:

Answer 8

CA125 and ultrasonography findings.

Question 9

____ is considered to be the modality of choice cancer who have an adnexal mass, the standard for oncologic imaging of the uterus.

Answer 9

MR

Question 10

__ is usually diagnosed in women younger than 30 years old.

Answer 10

Vaginal adenocarcinoma

Question 11

Cancers of the ____ are the most deadly type of gynecologic cancer.

Answer 11

ovaries

Question 12

The uterine appendages are collectively known as the:

Answer 12

adnexa

Question 13

Which of the following statements is true regarding ovarian cancer symptoms?

Answer 13

Advanced ovarian cancer might be asymptomatic.

Question 14

The Cancer Genome Atlas Project has shown that endometrial tumors might actually represent ___ genetically distinct tumor types.

Answer 14

4

Question 15

Patients who have stage ______ cancer rarely benefit from adjuvant radiation therapy.

Answer 15

I low-grade endometrial

Question 16

Endometrial cancer is the most common gynecologic malignancy.

Answer 16

True

Question 17

Patients who have advanced vaginal cancer might receive:
1. EBRT of involved inguinal lymph nodes.
2. EBRT of involved para-aortic lymph nodes.
3. brachytherapy.

Answer 17

1, 2 and 3

Question 18

Type ___________ tumoriogenesis involves unchecked estrogen stimulation.

Answer 18

I endometrial

Question 19

Patients with acute pelvic inflammatory disease should not undergo:

Answer 19

sonohysterography.

Question 20

The largest study to date on the subject failed to confirm association between _____ and ovarian cancer.

Answer 20

talc

Question 21

Which of the following factors increase endometrial cancer risks?

1.diabetes mellitus
2. tamoxifen administration
3. polycystic ovary disease

Answer 21

1, 2, 3

Question 22

Uterine carcinomas arise from ______ tissues.

Answer 22

epithelial

Question 23

o minimize the risk of toxicities associated with larger irradiated volumes in whole-abdomen radiation therapy, radiation dose is limited to
______ Gy at fractions of up to ______cGy.

Answer 23

30; 170

Question 24

Germ cell ovarian tumors represent ___% of diagnosed ovarian cancer cases.

Answer 24

5

Question 25

Lynch syndrome is associated with which of the following cancers?
1. endometrial
2. vaginal
3. colorectal

Answer 25

1 and 3

Question 26

Endometrial thickening is considered suspicious for endometrial cancer when measured on transvaginal sonography as greater than ______ mm, or as greater than ______ mm for postmenopausal women not on estrogen replacement therapy.

Answer 26

5;3

Question 27

______ is preferred for determining tumor depth and extent within the uterine tissues.

Answer 27

MR

Question 28

Which of the following statements is false regarding BRCA mutation?

Answer 28

Risk of gynecologic cancer with BRCA mutation is high regardless of the genomic location.

Question 29

____ women tend to be diagnosed at a later stage and grade of endometrial cancer than other patients.

Answer 29

Black

Question 30

Among postmenopausal women with ovarian cancer who have an adnexal mass, the standard treatment approach is:

Answer 30

surgery with histologic staging