*******Final Exam [4621]******** Flashcards
In which anatomical location are primary bone lesions most common?
Lower extremity
In which anatomical location are metastatic bone lesions most common?
Spine
In which anatomical location are soft tissue sarcomas most common?
Lower extremity
What is the most important prognostic factor for osteosarcoma?
Presence of metastatic disease
What type of bone marrow is contained in the diaphysis of long bones?
Yellow
What is the most common form of primary bone cancer?
Osteosarcoma
What is the most common site of metastasis from a primary bone cancer?
Lung
Which of the following is the most common metastatic site in STS?
Lung
When used with radiation therapy, which of the following reduces the loss of function and improves overall control?
Limb-sparing surgery
All except which of the following are examples of primary bone tumors?
Rhabdomyosarcoma
Which of the following has the highest incidence of bone tumors?
Metastatic bone lesions
Which of the following is the most common presenting symptom of patients with bone tumors?
Pain
The main shaft of a typical long bone is termed the __________.
diaphysis
The most common symptom associated with STS is __________________.
palpable and painless mass
A mantle field is used to treat which type of cancer?
Hodgkin’s disease (HD)
In what general anatomical location is Waldeyer ring located?
Mouth
The spleen is commonly associated with which of the following blood cell types?
Red blood cells
The thymus is commonly associated with which of the following blood cell types?
T-cell lymphocytes
The abdominal para-aortic treatment portal may include the________.
Spleen
What is the standard dose delivered for the treatment of non-Hodgkin’s lymphoma (NHL)?
3000 to 4500 cGy
What landmark is typically used to determine the lower border of the mantle field?
T10
What landmark is typically used to determine the lower border of the abdominal portion of the inverted-Y field?
L4-5
What is the most common presenting symptom of HD?
Painless mass
Which treatment field for HD includes the inguinal lymph node chain?
Inverted-Y (pelvic portion)
Which treatment field for HD includes the axillary lymph node chain?
Mantle
Which treatment field for HD includes the cervical lymph node chain?
Mantle
Which treatment field for HD includes the para-aortic lymph node chain?
Inverted-Y (abdominal portion)
Which treatment field for HD includes the retroperitoneal lymph node chain?
Inverted-Y (pelvic portion)
Which treatment field for HD includes the iliac lymph node chain?
Inverted-Y (pelvic portion)
Which treatment field for HD includes the mediastinal lymph node chain?
Mantle
Which of the following organs is most closely associated with the lymphatic system?
Spleen
Which of the following is not a B symptom?
Diarrhea
Today, the standard treatment for early stage Hodgkin lymphoma is combination chemotherapy and irradiation of the involved field to a dose of ____ Gy.
36
Cancer of which of the following endocrine glands has the highest incidence rate?
Thyroid
Cancer of which of the following endocrine glands is the most deadly?
Thyroid
In which gland is oxytocin produced?
Pituitary
In which gland is prolactin (PRL) produced?
Pituitary
In which gland is epinephrine produced?
Adrenal
In which gland is T4 produced?
Thyroid
Radioactive iodine is used to treat cancers of which of the following endocrine glands?
Thyroid
Radiation is a known risk factor for cancers of which of the following endocrine glands?
Thyroid
The pituitary gland is located within what portion of the sphenoid bone?
Sella turcica
What is the most common form of thyroid cancer?
Papillary
Which of the following is the primary thyroid tumor with the worst prognosis?
Anaplastic
Osteosarcomas are most commonly found in the _____________.
distal femur
Malignant plasma cells tumors are known as which of the following?
multiple myeloma
The rationale for leaving a 1-3cm strip of skin and soft tissue rather than total circumferential irradiation of an extremity being treated for STS includes:
avoids future excessive fibrosis and edema
The loss of differentiation is known as:
anaplasia
Which of the following is linked to HIV?
Kaposi’s sarcoma
A system of determining how much a cancer has spread from its original site is:
staging
A malignant tumor of fat would be called a(n):
liposarcoma
A malignant tumor of mesenchymal origin would be called a(n):
sarcoma
The most common histologic subtype of Hodgkin’s lymphoma is:
nodular sclerosing
Hodgkin’s lymphoma tends to predominately spread:
via lymphatic route in a contiguous manner
The endocrine gland that is approximately the size of a pea and located at the base of the brain is the
pituitary
The parathyroid glands are located
in the posterior aspects of the lobes of the thyroid gland
The endocrine gland, located above each kidney and divided into portions called the medulla and cortex, is the
adrenal gland
Which of the following modalities is used in treatment of microadenomas?
surgery
Which leukemia subtype is most common in children ?
ALL
What is considered the treatment of choice for all leukemias?
Chemotherapy
Which of the following is not a histologic subtype of leukemia?
CAL
Which of the following chemotherapy regimen(s) is/are used to treat Hodgkin’s disease? (Choose all that apply)
I. CHOP
II. MOPP
III. ABVD
II
III
tissue of origin of smooth muscle
leiomyosarcoma
tissue of origin of lymph vessels
angiosarcoma
tissue of origin is peripheral nerves
malignant schwannoma
tissue of origin of autonomic ganglia
neuroblastoma
tissue of origin of fibrous tissue
fibrosarcoma
tissue of origin cartilage
chondrasarcoma
tissue of origin of blood vessels
hemangiosarcoma
tissue of origin striated muscle
rhabdomyosarcoma
tissue of origin adipose tissue
liposarcoma
The papillae that separate the anterior 2/3 of the tongue from the posterior 1/3 is/are:
circumvallate
What is the most common symptom associated with childhood brain tumors in the cerebellum?
ataxia
The tonsils are located in the hypopharynx.
False
The node of Rouviere is also called the:
lateral retropharyngeal
Painful swallowing is also called:
odynophagia
Prognosis for cancer of the vocal cords is favorable due to:
no lymph node involvement
The pyriform sinus is located in the hypopharynx
True
What is the tumor staging system for lung cancer?
TNM
The inferior border of the larynx port for the vocal cords treatment anatomically corresponds to:
cricoid cartilage
What is the first treatment of choice for SCLC?
chemotherapy
What is the most common grade of gliomas?
high grade
Which is the TD 5/5 of the heart?
40 Gy
The ______ salivary gland located 2cm anterior and 2cm inferior to the EAM is:
parotid
What is the most common source of brain metastases among the following?
Lung
Which of the following is a characteristic of a benign tumor?
cells appear relatively normal
Which of the following structures is NOT in the oropharynx?
Hard palate
What is the most common form of larynx cancer?
squamous cell
Which of the following is a late effect of brain irradiation in children?
Decreased IQ
Which of the following is not associated with developing brain tumors?
smoking
Which of the following is/are common presenting symptoms of brain tumors in adults? (Choose all that apply)
blurred vision, headaches, seizures
Mesothelioma is a cancer of which respiratory system component?
Pleura
Which of the following terms is used to describe the surgical removal of an entire lung?
Pneumonectomy
obstruction, discharge, facial pain, dipolpia and local swelling are presenting symptoms associated with what location?
nose and sinuses
dysphagia and painful neck node are presenting symptoms associated with what location?
hypopharynx
swelling or an ulcer that fails to heal are presenting symptoms associated with what location?
oral cavity
bloody discharge and difficulty hearing are presenting symptoms associated with what location?
nasopharynx
painful swallowing and referred otalgia are presenting symptoms associated with what location?
oropharynx
hoarseness and stridor are presenting symptoms associated with what location?
larynx
The treatment of choice for head and neck carcinomas, that are inaccessible to a surgeon’s knife:
radiation therapy
A patient presents with positive Epstein-Barr virus and a painless neck mass. This is most likely a _____ cancer.
nasopharynx
The primary lymphatic drainage of the lower lip would be to:
submental nodes
Treatment fields in the chest should be designed
with respiratory motion in mind
What is the TD 5/5 for whole lung?
17.5 cGy
The area that contains the pyriform sinus, posterior cricoid cartilage and lower posterior pharyngeal wall is the:
hypopharynx
What is the most significant risk factor associated with mesothelioma?
Asbestos exposure
What defines the inferior radiation field border for the treatment of the whole brain for palliation?
Both b and c
What is the tumor staging system for lung cancer?
TNM
In what part of the lung are primary squamous cell carcinomas usually found?
Central
Which of the following is anatomically situated between the vertebral bodies C3 to C6:
hypopharynx
In which portion of the brain do most CNS tumors occur in pediatric patients?
cerebellum