Gynecologic Cancer Flashcards

1
Q

Which ovarian tumor, due to its location, most often spreads to the peritoneum and fallopian tubes?

A

Epithelial cell tumor

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2
Q

Most common symptom of uterine cancer

A

Postmenopausal bleeding

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3
Q

Two ways to screen for cervical cancer

A
  • Pap smear
  • HPV testing
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4
Q

Germ cell ovarian tumors are more common in [blank] women, whereas stromal cell ovarian tumors are more common in [blank] women

A
  • Germ cell: young women, <20
  • Stromal cell: postmenopausal women
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5
Q

Most common gynecologic cancer

A

Uterine cancer

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6
Q

Diagnosis method for uterine cancer

A

Endometrial biopsy

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7
Q

Three types of ovarian cancer and which is most common?

A
  • Epithelial cell most common
  • Germ cell
  • Stromal cell
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8
Q

Ovarian cancer is most often asymptomatic. If symptoms are present, they will most likely be …

A

Abdominal (GI/GU)
- Bloating
- Constipation
- Bladder symptoms

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9
Q

Age to begin cervical cancer screening and that cervical cancer screening can be ceased if all previous tests normal

A

Begin: 21
End: 65

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10
Q

Risk factors for uterine cancer

A
  • Increased estrogen exposure (early menarche, late menopause, nulliparity, chronic anovulation)
  • Lynch syndrome
  • Obesity
  • Tamoxifen therapy
  • Age (60-70)
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11
Q

Name of the sign where there is a sudden onset of seborrheic keratoses across the body

A

Leser-Trelat sign
- indicates presence of an internal malignancy (or that one is coming)

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12
Q

Risk factors for cervical cancer

A
  • Early age sexual intercourse (HPV)
  • Multiple male partners/male partners who have had multiple partners (HPV)
  • Smoking
  • Immunosuppression
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13
Q

Three types of gynecologic cancer

A
  • Ovarian
  • Cervical
  • Uterine
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14
Q

Explain LSIL/HSIL and CIN1/2/3 in relation to cervical cancer

A

LSIL = low grade squamous intraepithelial lesions = CIN1
- low risk, just monitor with annual pap smears

HSIL = high grade squamous intraepithelial lesions = CIN2/3
- high risk, remove the cells/tissue

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15
Q

Cervical cancer most common symptom

A

Postcoital bleeding

(possibly vaginal discharge, edema if advanced and blocking lymph)

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16
Q

Most common cause of cervical cancer

A

HPV infection

17
Q

Imaging method for ovarian cancer diagnosis

A

Transvaginal ultrasound

18
Q

97% of uterine cancers arise from this tissue

A

Endometrium

19
Q

Which gynecologic cancer is associated with monitoring of carcinoembryonic antigen (CEA) and CA125 tumor marker?

A

Ovarian cancer
- monitored to track success of therapy

20
Q

Four risk factors for ovarian cancer

A
  • Age (average = 60)
  • Family history (BRCA1 and BRCA2)
  • Estrogen exposure (like breast cancer)
  • Lynch syndrome (likely younger at dx, <50)
21
Q

Average age of cervical cancer patients

A

50-60

(premalignant lesions found <40)