GYN Flashcards
ovarian cysts
in postmenopausal women–> consider malignancy
bening: common in reproductive age
- many resolve on own
most common type is functional ( follicular test),
- resolve in 60 days
dx: sonogram
management: observation 30-60 days
- follicular or theca lutein- surgical evaluation is present
nonfunctional: endometraiona ( chocolate cyst)– surgery
PCOS
1 cause of androgen excess ad hirsutism
- bilat cysts
- presentation: hirsutism, infertility
- women with regular periods in young years and in 20s periods are very
sonogram/labs: string of pearls, oyster ovaries
elevated androgen, high FSH, LH, lipid abnormality , insulin resistant
tx: OCPs, DepoProvers, weight loss
if wants pregnancy:climid with metformin
ovarian cysts- neoplastic masses
bening neoplastic process
- serous cyst adenoma- -uniloular, most common
- bening cystic teratoma- mobile on long pedicles ( have teeth and hair)
mangement: surgery
ovarian cancer
2nd gyn malignancy
- mean age 69
RF: BRCA 1 gene, fix, nulliparity, late menopause, caucuasian/ asian, diet high in sat fat
screenin: biannual pelvic exam
- sonogram not done for routine screening
tumor types: epilethial
s/s: early - most asymptomatic
later: abd distenction, pain, early satiety, urinary frequency, change in bowel habits
exam: fixed, bilat nodualr pelvic mass, abd distenion, ascities, sister mary joseph’s nodule in the umbilicus
dx: sonogram, biopsy
tumor markers: CA 125 and CEA
tx: TAH/ SBO
chemo -IV or IP
-rad tx
Pap smear screening
who gets tested:
women under 21 should be tested regardless of sexual initiation
- 21-29- every 3 years
30-65- Pap and HPV every 5 years or Pap one every 3 years
over 65–> previous normal Paps- no testing
h/o pre-cancer- Paps 20 years after that dx
check for statement of adequacy: most have endocervical cells,
if adequate:
negative, atypical squamous cells, low grade spumous, or high grade , or cancer
management:
ASCUS- repeat 4-6 months, if second is same do colposcopy
ASC-H, LSIL, HSIL-colposccopy/ bx/ HPV testing
treat histology not pap results
CIN1- repeat in 6- 12 months
HPV DNA testing
CIN1 or C1N3- cryotherapy
cold knife conization, or LEEP
cervical cancer
3rd most common
RF: early sex, too man sex partner, HPV, smoking
16, 18, 31, 33
squamous cell
s/sx: post-coital bleeding
exam: cervix if friable
dx: pap and bx
tx TAH
Stage 3/ 4 chemo and rad tx
cytocele/ retocele/ uterine prolapse
common after menopause
- cystocele- prolapse of bladder into ant wall of vagina
- retocel- herniation of rectum into post wall
uterine prolapse- prolapse vaginal canal
sx: vaginal fullness or pressure, feeling of incomplete voiding/ defecation
tx: topical estrogen therapy ( cystocele)
- pessary
- kegel exercises
- surgcial repair
mastitis
- occurs inf breastfeeding women
- caused by nipple trauma
- s. aureus
sx: unlit, erytheamt, tenderness
- fever/ child
tx: dicloxacilin, cefalexin, erythro
- continue breast feeding on affected side
breast abscess
farther along mastitis
- localized mass
- f/c
management: I and D
IV abx- vancomycin
stop breastfeeding
pump and dump
fibrocystic breast
- sxs: painful cystic billet breast pain, size of cyst fluctuate during menstrual cycle
exam; bilat cysts that vary in size
sonogram- fluid filled cysts
tx: conservation, reduce caffeine, increase vitamin e, tamoxifen, or bromocritpin
fibroadenoma
- AA, 20 years of puberty
- painless and unlit
- mobile
s/s: painless uniat lump
dx: sonogram- smooth, uniform, solid, FNA ( no fluid)
-watched,
large- surgery
breast cancer
most common cause in women, 2nd MC cause of cancer
RF: BRCA 1 and 2
- prolonged use of unopposed estrogen
- early menarche, late menopause, late first pregnancy, nulliparty, over 40
- high fat diet
- obesity
- hyperplasia with fibrocystic breast
mammogram screening: If average risk: start at 40 40-40--> every 1-2 years > 50-- every year
Genetic RF: 25-35
not accurate
consider MRI
tumor types 80% infiltrating ductal
- painless, stony hard unlit mass
- infiltrating lobular- 10%
- inflammatory- 2%
- Paget’s dz- 1% ( rash on her breast and tried anti-fungal cream)
sx: painless mass in URQ, nipple d/x, erosion.
dx: 90% seen on exam u/s mammogram FNA open bx
surgery: 1 cm
hormone therapy-HR positive( tamoxifen and AI)
Zometa to dec fx
menopause
mean age 51
-low estrogen
changes: cessation of sense, hot flashes, dec vaginal lubrication, depression, mood swings
late changes: CAD
- everything dries up and falls down
FHS> 30 diagnostic
tx: HRT-contervial
used for hot flashes and dryness
CI: liver dz, thrombosis, CA of breast or endometrial
alternative tx:
hot flashes- depo vera, SSRI, yoga, acupuncture
osteopsosi: calc with vitamin d
vaginal dryness
vaginitis
candida: RF: HIV, DM, abx s/sx: thick white 10% KOH pseudonyme tx: diflucan po or single dose or azole cream
bacterial vaginosis
-smells bad, d/c worse after menses, scant/ sticky, clue cells,
flagyl 500 mg bid X 7 days
-think about cost
trichomonas - sexual awtiviy, copious d/c, green/ yellow frothy ( strawberry cervix), protozoa, flagyl 2 g po X 1 dose
flagyl- avoid ETOH and sun
chlamydia
most common of STI
RF: sex
gonorrhea
- vaginal itching or penile itching
- cervical motion tenderness
- dissementiated infection
- cause of septic arthritis ( wrist, elbows, knee, ankles)
- macular papular leions on hands and feet
tx: zithromax X 1 dose
or ceftrixome
tx partners
HPV
most common STI in women
- subtype 6 and 11 are being
16, 18, 31, 33- cause cervical cancer
-cauliflower -like warts on external genitalia, anus, cervical
dx: HPV DNA testing, clinical on PAP
tx: small lesions
-podophyllin, imiquimod
large lesions: cryotherapy or surgery
prevention gardais vaccine
girls and boys 9-26
16, 18,
pelvic inflame dz
- bacteria starts in uterus and works its way up bilat
pathogens: chlamydia- dos common, gonorrhea,
RF: age 20, prior PID, prior douche
sx: bilat pelvic pain, back pain down the legs
exam: mucopurlent cervical d/c
- cervical motion tenderness
dx: cervcial cx
- elevatd WBC
- sonogram
d/d: ectopic, appendicitis, pyelonephritis
tx: inpatient- pelvic access, fever above 102, pregnancy, unreliable pt
outpatient: ceftriazone IM single dose +doxcycyline po X 14 days
contraception
NPF- tracking a women menstrual cycle,
avoid sex 48 hours before and after this time
- check Basal body temp and monitor cervical mucous
failure rate: 25%
barrier methods “
condoms- protects gains STI, diaphragm ( bladder irritation), cervical cap
, spermicides
advantage: low SE profile, low cost
hormonal method
estrogen and progesterone - 3 weeks and 1 week off ( get periods
monphasic- dose is stay
-advantage- in monogamous relationship
OrthoEva- path changed once a week X 3 weeks
failure rate 1%
Nuva Ring-
leave in for 3 weeks and then come out for menses
- estrogen suppress FSH so follicle won’t mature
- no ovulation
- mucous is thicker
benefits: dec endometrial can, ovarian cyst, dysmneoorhea, fiber breast
CI: pregnancy, H/o: dat, breast/ endometrial cancer, melanoma, abn liver function tests
progesterone only
- taken daily
- take same time every day
- good breastfeeding
- women > 40
Depo Provea- IM every 3 months - return of ovulation up to 18 months ( good for teenagers) SE: weight gain, mood changes, only use for 2 years calcium loss
SQ Rods: left 3-5 years
cannot take oral
ovulation start promptly after removal
SE: scarring
- MOA: ovulation interrupted
CI: breast ca and liver tumors
IUD
replace every 5-10 years -wire in winning of future -multi-parous women - smokers > 35 y/o CI: pregnancy, uterine bleeding, acute gyn infection,
complications: uterine perforation,