GU Flashcards
type of diuretic is triamterene
k sparing
type of diuretic is acetazolamide
carbonic anyhydrase inhibitor
type of diuretic is HCTZ
thiazide
type of diuretic is bemetanide
loop
type of diuretic is spironolactone
k sparing, aldo antag
type of diuretic is ethacrynic acid
loop
type of diuretic is mannitol
osmotic
type of diuretic is metolazone
thiazide
type of diuretic is chlorthalidone
thiazide
type of diuretic is furosemide
loop
type of diuretic is amiloride
K sparing
type of diuretic is torsemide
loop
diuretic used for acute pulmonary edema
loop
diuretic used for idiopathic hypercalciuria
thiazide
diuretic used for glaucoma
acetazolamide / mannitol
diuretic used for mild to moderate CHF with expanded ECV
loop, aldo antag
diuretic used for with loop or thiaziode to retain K
K sparing
diuretic used for edema associated with nephrotic syndrome
loop
diuretic used for increased intracranial pressure
acetazolamide / mannitol
diuretic used for mild to moderate hypertension
thiazide
diuretic used for hypercalcemia
loop
diuretic used for altitude sickness
acetazolamide
diuretic used for hyperaldosteronism
spironolactone, eplerenone
bacteria causing pyelonephritis
e coli, saprophyticus, proteus, klebsiella, candida
medical management of renal stone
IV hydration, pain meds, (?) tamsulosin/ nifedipine
treatment for uric acid renal stones
alkalinize urine with Na citrate or sodium bicarb
size calcium renal stone has 50% likelihood of passing without surgical intervention
8-9 mm
five etiologies of temporary hematuria
UTI, trauma, nephrolithiasis, exercise, endometriosis
renal pathology from uncorrected severe benign prostatic hyperplasia
bilat hydronephrosis
cardiac abnormalities associated with ADPKD
MVP, aortic regurgq
biggest risk factor for renal cell carcinoma
smoking
patient involved in MVA has a crushed thigh. Your resident says give patient IV fluids to maimtain high urime output of 100-200. Why did she advise this?
to prevent interstitial nephropathy from increased myopathy
what is the most common cause of interstitial nephropathy/ nephritis?
drug
NSAID, aminoglycoside, beta lactam, sulfonamides
50 y/o smoker presents with flank pain, weight loss, hematuria, and polycythemia. What is the next step?
imaging of kidneys
renal pathology with IF: granular pattern of immune complex deposition, LM: hypercellular glomeruli
post infectious
renal pathology with linear pattern of IgG deposition
goodpasture
renal pathology with anti GBM antibodies, hematuria, hemoptysis
goodpasture
renal pathology with nephritis, deafness, cataracts
alport
renal pathology with LM: crescent formation in the glomeruli
RPGN
renal pathology with palpable purpura on back of arms and legs, abdominal pain IgA nephropathy
HSP
renal pathology with positive ANCA
pauci immune RPGN, granulomatosis with polyangiitis
renal pathology with anti dsDNA antibodies
lupus nephritis
defining features of nephrotic syndrome
proteinuria > 3.5
albumin less than 3
edema
glomerular histology reveals multiple mesangial nodules. This lesion is indicative of what disease?
DM nephropathy
renal pathology with most common nephrotic syndrome in children
minimal change disease
renal pathology with most common nephrotic syndrome in adults
FSGS
renal pathology with EM: loss of epithelial foot processes
minimal change disease
renal pathology with nephrotic syndrome associated with hepatitis B
membranous
renal pathology with nephrotic syndrome associated with HIV
FSGS
renal pathology with EM: subendo humps and tram-track appearance
MPGN
renal pathology with LM: segmental sclerosis and hyalinosis
FSGS
renal pathology with EM: spike and dome pattern of the basement membrane
membranous
renal pathology with most common nephrotic syndrome in AA males
FSGS
renal pathology with apple green birefringence with Congo red stain under polarized light
amyloidosis
patient is found to have fever, rash, elevated creatinine, and eosinophilia. Dx?
AIN
In prerenal acute renal failure what is the value for fractional excredtion of sodium? For BUN:creatinine ratio?
FENa less than 1
BUN: creatinine greater than 20
Which test is used for screening diabetic patients for kidney damage?
urine microalbumin
what blood pressure medications are renal protective and preferred in the treatment of HTN in patients with chronic kidney disease?
ACEI/ARB
RTA Type 1: urine pH, serum K, serum HCO3
urine pH > 5.3
serum K decr
serum HCO3 decr
RTA Type 2: urine pH, serum K, serum HCO3
urine pH less than 5.3
serum k decr
serum hco3 decr
RTA Type 4: urine pH, serum K, serum HCO3
urine pH less than 5.3
serum k incr
serum hco3 nl
treatment of Type I RTA
sodium bicarb, K, thiazide
treatment of Type II RTA
sodium bicarb, K, thiazide
treatment of Type IV RTA
fludrocortisone, restrict K
Common cause of metabolic alkalosis
vomiting, diuretics, hyperaldo, cushing
common cause of respiratory alkalosis
hyperventilation
- high altitude, asthma, aspirin tox, PE
common cause of respiratory acidosis
COPD, resp depression, NM disease
common cause of anion gap metabolic acidosis
MUDPILES
methanol uremia DKA propylene glycol INH/iron lactic acidosis ethylene glycol salicylates
common cause of nongap metabolic acidosis
diarrhea, hypoaldo, RTA, TPN
What is the consequence of correcting hyponatremia too rapidly? How rapidly can it safely be corrected?
central pontine myelinolysis
volume status in patient with hyponatremia from thiazide
hypovolemic
volume status in patient with hyponatremia from SIADH
euvolemic
volume status in patient with hyponatremia from cirrhosis
hypervolemic
volume status in patient with hyponatremia from addison disease
hypovolemic
volume status in patient with hyponatremia from hypothyroidism
euvolemic
volume status in patient with hyponatremia from renal failure
hypervolemic
volume status in patient with hyponatremia from psychogenic polydipsia
euvolemic
most common causes of SIADH
CNS disease, pulmonary disease, drugs, HIV/AIDS, abdominal surgery
consequence of correcting hypernatremia too rapidly? how rapidly can it safely be corrected?
cerebral edema
next step in the management of a patient with peaked T waves on EKG due to hyperkalemia
IV ca gluconate/ CaCl
medications used to rapidly correct hyperkalemia by shifting potassium into cells
insulin and glucose
sodium bicarb
albuterol
treatment for nephrogenic DI
increased H20, salt restriction, thiazide, indomethacin
Li induced nephrogenic DI - amiloride
medications are known for causing hyperkalemia? hypokalemia?
K sparing diuretics, ACEI, ARB, beta blocker, dig
diuretics, albumin, insulin
which electrolyte abnormality causes QT prolongation on EKG? which electrolyte abnormality causes QT shortening?
hypocalcemia
hypercalcemia
which type of RTA is associated with abnormal HCO3 and rickets
RTA 2
risk factors for developing bladder cancer
smoking, schistosomiasis, aniline dyes, recurrent UTIs, male, cyclophosphamide
what are the three types of urinary incontinence
urge, stress, overflow
diagnostic tests will confirm diagnosis of overflow incontinence
bladder US
post void cath
first step in treating bladder outlet obstruction
decompress bladder with foley
diagnostic test differentiates normal central DI from nephrogenic DI
ADH test
what is the treatment for urethritis in men
cef, doxy/azithro
classic symptoms of BPH
weakened urinary stream, urinary retention, frequency, nocturia, urgency
two classes of medications are used most often to treat BPH
alpha 1 antagonist
5alpha reductase inhibitor
hormonal medicatioins are often given to patients with metastastatic prostate cancer
GnRH agonist
- leuprolide, geserelin
treatment for epididymitis
under 35 cef, doxy/azi
over 35 fluoroquinolones
most common germ cell tumor of the testis
seminoma
lab work included in the workup for erectile dysfunction
total testosterone
prolactin
TSH
+/- PSA
what is the most common physical finding/presenting symptom of a child with wilms tumor
renal flank mass
4 year old boy diagnosed with a UTI. What study should be performed next?
voiding cystourethrogram
recommended therapies for nocturanl enuresis?
toilet training, motivation, fluid restriction, enuresis alarm, DDAVP
male newborn with distended palpable baldder and oliguria. What is the most common cause of congenital urethral obstruction
posterior urethral valves
25 y/o male with solitary testicular mass by ultrasound. Next step?
surgical excision
signs and symptoms of pyelonephritis?
dysuria/frequency/urgency flank pain fever/chills N/V CVAT
test used to rule out urethral injury?
retrograde cystourethrogram
Patient has palpable flank mass and hematuria and renal ultrasound shows bilateral enlarged kidneys with cysts. What brain anomaly is associated with this condition?
Berry aneurysms
Patient has eosinophilic casts found in the urine. Dx?
AIN, drug reaction
Man presents with acute onset flank pain and hematuria. What is the most likely etiology?
kidney stone
Postop patient has poor urine output, BUN 85, creatinine of 3 and clear lungs. What is the next step in management of this patient?
IV fluids
Patient with glomerulonphritis plus bilateral sensorineural deafness. What is the diagnosis?
alport syndrome
Post op patient with significant pain presents with hyponatremia and normal volume status. What is the diagnosis?
SIADH
glomerular disease with IF granular pattern of immune complex deposition; LM: hypercellular glomeruli
acute post strep GN
glomerular disease with IF: linear pattern of immune complex deposition
goodpasture
glomerular disease with EM: loss of epithelial foot processes
minimal change disease
glomerular disease with EM: subendothelial humps and “tram track” appearance
MPGN
glomerular disease with nephritis, deafness, cataracts
alport syndrome
glomerular disease with purpura on the back of hte arms and legs, abd pain, IgA nephropathy
HSP
glomerular disease with anti-dsDNA antibodies
lupus nephritis
What is the classic presentation of poststrep glomerulonephritis?
child with brown urine and HTN
strep 1-3 weeks prior
high ASO titer
30 year old female african immigrant presents with hematuria. What do you suspect in this patient?
schistosoma haematobia
treatment for epididymitis?
cef and doxy/azi
medications used in the treatment of wegener’s granulomatosis?
steroids
cyclophosphamide