Gastroenterology Flashcards
infectious agent causing food poisoning as a result of mayo sitting out too long
s aureus
infectious agent causing rice water stools
v cholera
infectious agent causing diarrhea transmitted from pet feces
y enterocolitis
infectious agent causing food poisoning resulting from reheated rice
b cereus
infectious agent causing travelers’ diarrhea
e coli (ETEC)
infectious agent causing diarrhea after course of abx
c diff
infectious agent causing diarrhea and recent ingestion of water from a stream
giardia, e histolytica
infectious agent causing mild intestinal infection that can become neurocysticercosis
t solium
infectious agent causing food poisoning from undercooked hamburger
e coli (EHEC)
infectious agent causing diarrhea from seafood
v parahaemolyticus
infectious agent causing bloody diarrhea from poultry
salmonella
infectious agent causing diarrhea and pink eye
adenovirus
infectious agent causing bloody diarrhea and liver abscess
e histolytica
infectious agent causing diarrhea in AIDS patient
crypto
infectious agent causing dehydrated child with greenish diarrhea in winter months
rotavirus
treatment of e histolytica
metronidazole
treatment of giardia lamblia
metronidazole
treatment of salmonella
fluoroquinolones
treatment of shigella
fluoroquinolones, TMP-SMX
treatment of campylobacter
erythromycin
hepatitis virus confers a high risk of chronic hepatitis
hep C
hepatitis virus confers high risk of hepatocellular carcinoma
hep B
treatment of hep C
interferon alpha
ribavirin
Hep BsAg negative
HepBsAb negative
Hep BcAb positive (IgM)
window period
Hep BsAg positive
Hep BsAb negative
Hep BcAb positive (IgG)
chronic infection
Hep BsAg negative
Hep BsAb positive
Hep BcAb negative
vaccine
Hep BsAg negative
Hep BsAb positive
Hep BcAb positive (IgG)
past infection
next step after H&P for patient complaining of dysphagia
barium swallow
treatment for diffuse esophageal spasm differ from that of achalasia
DES - medically, nitrates and CCBs
achalasia - surgical intervention, dilation, botox, myotomy
esophageal disorder which involves CP; uncoordinated contractions; corkscrew pattern on barium swallow
diffuse esophageal spasm
esophageal disorder which involves inability to relax the LES; bird’s beak on barium swallow
achalasia
esophageal disorder which involves bad breath; regurgitation of food eaten days ago
zencker diverticulum
common symptoms of GERD
heartburn
bad taste in mouth
persistent cough
gastric ulcer timing and effect of eating
right after intake of food
worse with nausea and vomiting
duodenal ulcer timing and effect of eating
2-4 hours after food
better with food
effective treatment of duodenal ulcer, not from zollinger ellison syndrome
PPI
amox
clarithromycin
treatment for gastric cancer
distal 1/3 - subtotal gastrectomy
middle/upper - total gastrectomy
chemo/radiation as needed
female patient has known duodenal ulcer refractory to high dose PPI therapy. What two tests may diagnose her disease?
fasting gastrin
secretin stimulation test
oral infection has branching rods when examined microscopically
actinomyces
malabsorption in a patient with (+) sudan stain in stool sample and normal D-xylose test
pancreatic insufficiency
treatment for whipple disease
ceftriaxone
TMP-SMX
tumors causing secretory diarrhea
VIPomas
gastrinoma
med thyroid
carcinoid
two most common food borne bacterial GI tract infections in US
salmonella, c jejuni
Which form of IBD causes perianal fissures and fistulas
Crohn’s
serum lab findings might help distinguish Crohn’s from UC
antisaccharomyces cerevisiae - Crohn
pANCA - UC
most common cause of large bowel obstruction
neoplasm
treatment for Crohn’s disease
steroids
azathioprine
anti TNFalpha agents
signs and symptoms NOT associated with IBS
weight loss, fever, rectal bleeding, anorexia, worsening pain
Characteristic symptom of acute mesenteric ischemia
pain out of proportion to exam
CT scan imaging shows what for ischemic colitis
pneumatosis coli
bowel wall thickening
time frame in which post-op ileus resolves for small bowel
24 hours
time frame in which post-op ileus resolves for stomach
time frame in which post-op ileus resolves for colon
3-5 days
risk factors for diverticulosis
low fiber, high fat diet
increased age
treatment for mild diverticulitis
bowel rest
abx: cipro + metro
treatment for diverticulitis with abscess formation
perc drainage
IV abx
next step in management of patient younger than 50 with minimal bright red blood per rectum
anoscopy
cause of acute pain and swelling of midline sacrococcygeal skin and subq tissues
pilonidal cyst
gene responsible for familial adenomatous polyposis
APC
Common etiologies of upper GI bleeds
ulcer esophageal varices AVM tumors erosions mallory-weiss tears
common etiologies of lower GI bleeds
diverticulitis neoplasms ischemia hemorrhoids rectal fissures
volume status assessment in patient with GI bleed
vital signs
HR, BP, urine output
difference between mallory-weiss tear and boerhaave tear
mallory-weiss tear - laceration superficial in esophageal mucosa
boerhaave - perforation/tear, full thickness
ranson criteria for acute pancreatitis on admission
GA LAW
glucose > 200 AST > 250 LDH > 350 age > 55 WBC > 16,000
ranson criteria for acute pancreatitis in first 48 hours
CALvin and HOBBeS
calcium 10
pO2 4
BUN > 5
sequestration of fluid > 6
treatment for chronic pancreatitis
stop alc/smoking
pancreatic enzymes
fix nutrition
surgical repair
two most common cause of acute pancreatitis in US
gallstones
alcohol
procedure to treat cancerous tumor in head of pancrease
whipple procedure
signs and symptoms suggestive of pancreatic adenocarcinoma
painless jaundice, anorexia, wt loss, nausea, vomiting, palpable nontender GB
medication used to stop insulin production in patient with insulin producing pancreatic tumor
octreotide
symptom is the most common presentation of a patient with VIPoma
watery diarrhea
patient presents with dysphagia and the barium swallow shows a corkscrew pattern of esophagus. Dx?
diffuse esophageal spasm
patient presents with dysphagia and barium swallow shows bird’s beak sign in distal esophagus. Dx?
achalasia
type of patient at risk for acalculous cholecystitis?
TPN
critically ill
What is charcot’s triad? What is reynold’s pentad?
Charcot: RUQ pain, jaundice, fever
Reynold’s: RUQ pain, jaundice, fever, AMS, hypotension
treatment of cholecystitis
cholecystectomy
treatment of cholangitis
drain bile ducts, fluids and IV abx, wait for cholecystectomy
most common cause of travelers diarrhea
e coli (ETEC)
medical treatment for ulcerative colitis
5 ASA (mesalamine, sulfasalazine)
acute: steroids
what distinguishes primary biliary cirrhosis from primary sclerosing cholangitis?
PBC: women, autoimmune with RA, Sjogrens, CREST, intrahepatic bile duct, treatment ursodeoxylic acid, labs AMA, ANA
PSC: men, associated with UC, intra/extrahaptic bile duct, treatment liver transplant, labs pANCA, associated with cholangiocarcinoma, ERCP shows beads on a string
treatment for primary biliary cirrhosis
ursodeoxycholic acid, liver transplant
Sign and disease with deep palpation of RUQ, arrest of inspiration due to pain
murphy sign
cholecystitis
Sign and disease with charcot’s triad, hypotension, AMS
reynold’s pentad
cholangitis
Sign and disease with RLQ pain on passive extension of hip
psoas sign
appendicitis
Sign and disease with RLQ pain on passive internal rotaiton of flexed hip
obturator sign
appendicitis
Sign and disease with LUQ and referred left shoulder pain
Kehr’s sign
splenic rupture
Sign and disease with ecchymosis of skin overlying flank
gray turner sign
pancreatitis
Sign and disease with ecchymosis of skin overlying periumbilical area
cullen’s sign
pancreatitis
treatment for hepatic encephalopathy
lactulose, rifaximin
antibiotics used to treat spontaneous bacterial peritonitis
cefotaxime, ceftriaxone
two diuretics used in conjunction for the treatment of ascites/portal HTN
furosemide and spironolactone
symptoms of budd-chiari?
ascites
hepatomegaly
jaundice
RUQ pain
25 year old man with abdominal pain, watery diarrhea after meals. Exam shows fistulas between bowel and skin as well as nodular lesions on tibias. Dx?
Crohns
most widely used screening test for hemochromatosis
ferritin (increased)
what copper related lab value would you order with someone with wilson disease?
serum ceruloplasmin (low)
treatment for hemochromatosis?
phlebotomy, avoid excess alcohol, deferoxamine
location of zenker diverticulum, epiphrenic diverticulum, traction diverticulum
zenker: above UES
epiphrenic: above LES
traction: mid esophagus
most common type of TE fistula
upper esophagus ends in blind pouch
lower esophagus attached to trachea
classic presenting scernario for NEC
poor feeding, abd distention, bloody stools, pneumatosis intestinalis
physiologic jaundice - age, t bili, cause, tx
2-3 d,
breastfeeding - age, t bili, cause, tx
breast milk - age, t bili, cause, tx
> 1 week, > 5.5, unknown factor in milk, resolves on own
tx for a rectal fistula
fistulotomy
patient with cirrhosis presents to the ER to have his recurrent ascites drained. Analysis of the ascites fluid reveals an absolute neutrophil count > 250. What is the diagnosis?
SBP
What is light’s criteria? What is it for?
exudative effusion
pleural fluid protein: serum protein > 0.5
pleural fluid LDH: serum LDH > 0.6
protein > 3 g
tumor marker used in colon cancer
CEA
which type of esophageal cancer is most prevalent in the US?
adenocarcinoma
Next step in diagnosis of cholecystitis when the ultrasound is equivocal?
HIDA
45 year old obese woman with pruritus, clay colored stools and dark urine has an elevated alk phosph and elevated bili. What is the most likely cause?
biliary obstruction
24 year old woman with elevated BP. Good BMI, good diet, exercises, and does not smoke or use BC. What might be the cause of her HTN? What might be seen on radiological imaging?
fibromuscular dysplasia
beads on a string
tumor marker most useful in diagnosis of pancreatic cancer
CA 19-9
which form of IBD would you see a “lead pipe” appearance on barium enema?
UC
Ranson criteria for pancreatitis on admission
GA LAW
glucose AST LDH age WBC count
Ranson criteria for pancreatitis
CALvin and HOBBeS
calcium Hct O2 BUN base deficit sequestration of fluid
2 disorders should come to mind when a neonate has meconium ileus
CF
hirschsprung
tx for entamoeba histolytica
metronidazole
tx for giardia lamblia
metronidazole
tx for salmonella
quinolone or TMP-SMX
tx for shigella
quinolone or TMP-SMX
tx for campylobacter
erythromycin
what is charcot’s triad in cases of cholangitis?
fever, RUQ pain, jaundice
Patient suspected of having gastric cancer. During the physical exam you palpate in two places for enlarged lymph nodes associated with this disease. Where will you palpate and what are the names of the enlarged nodes?
virchow’s node - left supraclavicular
sister mary joseph - periumbilical
2 year old boy presents with painless rectal bleeding. What diagnosis do you suspect and what study would you order to confirm the diagnosis?
meckel’s diverticulum
meckel’s scan
what is the treatment for mild unconj hyperbilirubinemia in a neonate? Sever unconj hyperbilirubinemia in a neonate?
phototherapy
phototherapy or exchange transfusion
3 year old girl presents with abdominal mass, hematuria, HTN. What is the most likely diagnosis?
wilms tumor
cuban immigrant presents with symptoms of malabsorption is found to have megaloblastic anemia. Dx and tx?
tropical strue
treatment: folate, tetracycline
Elderly woman with a history of cholelithiasis presents with a 5 day history of vague intermittent abdominal pain and vomiting. Dx?
gallstone ileus
Treatment for whipple disease?
TMP-SMX for 1 year, ceftriaxone
Medications are used in the treatment of ileus?
metoclopromide, erythromycin, neostigmine
What is the most sensitive and specific lab test for the diagnosis of chronic pancreatitis?
low fecal elastase
Antibiotic combinations used in outpatient treatment of diverticulitis?
cipro/metro
bactrim + metro
amox-clav
Elevated lab in patients with an upper GI bleed?
BUN