Growth and puberty Flashcards
what are factors that can influence q child’s growth
genetic potential nutritional intake endocrine rgulation comorbidities emootional health
how do you assess growth in the UK
measure height (>2yo) OR length (<2yo) + weight + head circumference (in infants)
Plot on UK-WHO chart
Different charts for girls, boys, trisomy 21
when do you correct growth for prematurity until
until 2 yo
when do you start tracking centiles for babies
from birth
what about centiles will concern you in a baby
if the baby crosses 2 or more centile iness
how much of their birthweight is it normal for babies to lose in their first 10 days of life
10% max
what is the order of development of puberty in girls
thelarche (breast development) > adrenarche (pubic hair) > menarche (menstruation)
what do you call breast development
thelarche (mnemonic: tette)
what do you call pubic hair development
adrenarche (Axillary, pubic hair growth)
when i the average age for menarche
12.5 years
what is the rage of age for puberty in females, and the average age
8-13 yo
average: 11
when does puberty develop in males compared to females
18 months after females
what is precocious pubry
secondary sex characteristics developing at <8 years in girls and <9 years in boys
what are causees of precocious puberty
Central (GnRH dependent)
- idiopathic
- familial
- CNS tumour (e.g. optic glioma with NF1)
- developmental abnormality
- encephalitis, brain abscess
- hydrocephalus
Peripheral (GnRH independent)
- increased androgen secretion (CAH, leidig cell adenoma)
- gonadotrophin secreting tumour
- Ovarian cyst
- McCune-Albright syndrome
- iatrogenic / exogenous sex hormones
What are causes of global developmental delay
Antenatal:
- GENETIC (Downs, NF, Fragile X, Duchenne muscular dystrophy, TS)
- METABOLIC/ENDO (hypothyroid, PKU, MCAD)
- Toxin: drugs, alcohol
Perinatal/PN:
- infection
- trauma/ischaemia> cerebral palsy
- neglect