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P2: Bacteriology > Gram – Negative Zoonotic Rods > Flashcards

Gram – Negative Zoonotic Rods Flashcards

1
Q

4 medically important genera:

A

Brucella
Pasteurella
Francisella
Yersinia

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2
Q

Reservoir: cows

A

B. abortus

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3
Q

Reservoir: goats

A

B. melitensis

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4
Q

Reservoir: goats

A

B. melitensis

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5
Q

Reservoir: pigs

A

B. suis

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6
Q

Reservoir: dog

A

B. canis

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7
Q

Virulence Factors of Brucella spp.

A
  1. Capsule
  2. Tropism to erythritol
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8
Q

Transmission:

  1. Direct contact with contaminated livestock or aborted placentas.
  2. Ingestion of infected milk.
  3. Inhalation of organisms.
A

Brucella spp.

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9
Q
  1. Diurnal fever – “Undulant fever”
  2. Non – specific signs and symptoms
    - weakness - sweats
    - anorexia - malaise
  3. Organomegaly – splenomegaly, hepatomegaly and lymphadenopathy
A

Brucellosis/ Bang’s Disease

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10
Q

Induces abortion in animals

A

Brucella spp.

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11
Q

Rod to coccoid –shaped, arranged singly or in pairs –“appearance
of a sand”

A

Brucella spp.

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12
Q
  • slow growing
  • growth enhanced by 5 to 10 % CO2
A

Brucella spp.

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13
Q

Culture for Brucella spp.

A

i. Blood Agar Plate (BAP) – incubate for 4- 6weeks
ii. MacConkey Agar
iii. Brucella Agar

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14
Q

• Facultative anaerobe
• Non – motile
• Range morphologically from coccobacilli to long filamentous rods
• Found as commensals in the upper respiratory tract of fowl and mammals

A

Pasteurella spp.

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15
Q

most important human pathogen of Pasteurella spp.

A

Pasteurella multocida

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16
Q

Virulence factor of Pasteurella multocida

A

Capsule

17
Q

Transmission of Pasteurella multocida

A

From dog or cat bites

18
Q

gram – negative short rod with bipolar staining

A

Pasteurella multocida

19
Q

Culture:
- rarely grown on gram – negative differential media (EMB or MacConkey)
- grow on Blood Agar (BAP) may have musty or mousy odor

A

Pasteurella multocida

20
Q

Biochemical tests of Pasteurella multocida

A

Catalase = +
Indole = +
Oxidase = +
ONPG – Negative
Penicillin susceptible

21
Q

Biochemical tests for Pasteurella multocida

A

Catalase = +
Indole = +
Oxidase = +
ONPG – Negative
Penicillin susceptible

22
Q

Reservoir:
- Cottontail rabbit – primary reservoir
- both wild and domesticated animals
- birds
- arthropods
- also in water, muds, and animal feces

A

Francisella tularensis

23
Q

Transmission:
1. Tick bites
2. Inhalation
3. Ingestion
4. Direct contact with infected animals

A

Francisella tularensis

24
Q

Clinical manifestations:
Causes Tularemia
Ulceroglandular – at the site of inoculation

A

Francisella tularensis

P2: Bacteriology (11 decks)

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