Gout Flashcards
gout results from deposition of what in the synovium?
uric acid
what indicates chronic deposition of urate?
tophi
in gout what would you see under microscope?
negatively bifringent needle shaped crystals
what is first line for acute gout?
NSAIDS
what is second line in gout
colchicine
side effect of colchicine?
D+V colosseum
what kind of medication is allopurinol
xanthane oxidase inhibitor
why is allopurinol not given in the acute setting?
it can exacerbate acute attacks
what can be given if allergic to allopurinol?
febuxostat
what is a uricosuric
drug that increases the excretion of uric acid in the urine
examples of uricosurics?
- Sulfinpyrazone
- Probenicid
- Amplodipine
- Losartan
- Fenofibrate
what are uricosurics used for in gout
preventative
what kind of crystals do you get in psuedogout?
calcium pyrophosphate
what condition is psuedogout associated with?
OA
what is mono arthritis?
inflammation of one joint at a time
