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MS > Gout > Flashcards

Gout Flashcards

0
Q

3 types crystal induced arhtrits

A

gout
CPPD
BCP

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1
Q

crystal induced arthritis

A

articualr disease mediated by metabolic changes related to deposition of crystals within joint or periarticular tissue

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2
Q

who rarely gets gout?

A

premenopausal women

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3
Q

uric acid in gout

A

> / 6.8 mg/dl

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4
Q

what is increase uric acid due to

A

increase in purine breakdown

decrease in excretion (more common)

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5
Q

what elevates uric acid

A

meds (thiazides limit excretion)
iatrogenic (tumor lysis syndrome)
alch (beer >liquor>wine)

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6
Q

gout is classified as

A

mono/oligoarthritis –>resolves in seven days

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7
Q

podagra

A

hot, swollen, painful

MTP cmmon

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8
Q

tophi

A

clusters or cocentrations of gouty depositions

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9
Q

stage I of gout

A

asymp hyperuricemia

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10
Q

stage 2 of gout

A

acute intermittent arthritis

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11
Q

stage 3 of gout

A

chornic arthritis with acute exacerbations

**may see tophi and cartilage

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12
Q

gout acute tx

A

indomethacin (NO in RF)
steroids (systemic or local)
colchicine (not strong enough)–caution in RF

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13
Q

decrease fq flairs

A

colchicine

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14
Q

decrease fq flairs/UA crystals

A

allopurinol- stop during acute attack (skin rash, caution in RF)
probenecid (increase UA secretion- not great, lots of side effects)

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15
Q

you can increaase allopurinol

A

even when UA is in normal range

16
Q

febuxostat

A

people in RF can take thsi isntead of allopurinol, but its very expensive

17
Q

CPPD favors

A

bigger jts (knees, ankles, wrists)

18
Q

dx CPPD

A

aspiration

19
Q

xrays in CPPD

A

can see chrondrocalcinosus (ca in cartilage)

20
Q

acute Tx of CPPD

A

rest, nsaids, steroids, colchicine

21
Q

colchicine in CPPD

A

sometimes given prophylactically

22
Q

BCD aka

A

calcific tendititis/bursitis, hydroxyapatite disease

23
Q

dx of BCP

A

calcific tenditis, acute or chronic synovitis (harder to dx because unable to see crystals without special stain)

24
Q

treatment of BCP is the same as

A

tx of CPPD

MS (19 decks)

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