gonads Flashcards

oral contraceptive pill: identify the main components of combined oral contraceptives (COCs), explain their mechanism of action, list the unwanted side effects, and compare and contrast with post-coital (emergency) contraception and progesterone-only pill (POP)

1
Q

what is used in combined oral contraceptive

A

oestrogen (ethinyl oestradiol) and progestogen

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2
Q

2 examples of pregestogens in combined oral contraceptive

A

levonorgestrel, norethisterone

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3
Q

effects of combined oral contraceptive on ovulation and how

A

suppress ovulation; oestrogen and progestogen exert negative feedback actions at hypothalamus and pituitary, progestogen thickens cervical mucus (more difficult for sperm to penetrate)

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4
Q

combined oral contraceptive: how often do you take

A

take for 21 days, stop for 7 days

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5
Q

when would someone take a progesterone only contraceptive

A

when oestrogens contra-indicated

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6
Q

progesterone only contraceptive: when would oestrogens be contra-indicated

A

smoker, >35 years old, migraine with aura

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7
Q

why must progesterone only contraceptive be taken at the same time each day

A

short half-life and short duration of action

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8
Q

progesterone only contraceptive: how might long acting preparations be given

A

via an intra-uterine system

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9
Q

3 types of emergency (post-coital) contraceptions

A

copper IUD (intra-uterine contraceptive device), levonorgestrel, ulipristal

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10
Q

what must be excluded before using copper IUD (intra-uterine contraceptive device)

A

pregnancy

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11
Q

what does copper IUD (intra-uterine contraceptive device) affect in sperm

A

viability and function

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12
Q

effectiveness of copper IUD (intra-uterine contraceptive device) in overweight/obese women

A

not reduced

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13
Q

when can a copper IUD (intra-uterine contraceptive device) be used

A

5 (up to 7) days after unprotected intercourse

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14
Q

when must levonorgestrel be given

A

within 72 hours of intercourse

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15
Q

when must ulipristal be given

A

up to 120 hours after intercourse

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16
Q

3 effects of ulipristal

A

anti-progestin activity, delay ovulation by as much as 5 days, impairs implantation