appetite Flashcards
obesity epidemic: recall theories which aim to explain the obesity epidemic in the context of the homeostatic control of energy balance
10 comorbidities of obesity
depression, stroke, sleep apnoea, myocardial infarction, hypertension, diabetes, bowel cancer, osteoarthritis, peripheral vascular disease, gout
monozygotic (genetically identical) vs dizygotic (not genetically identical) twins: body mass
less correlation in dizygotic twins, so in given environment genetics have huge impact
thrifty gene hypothesis, and weakness in it
specific genes selected for in evolution to increase metabolic efficiency and fat storage, but in context of plentiful food and little exercise predispose carriers to obesity and diabetes; doesn’t expain why everyone isn’t obese
adaptive drift hypothesis
normal distribution of body weight, with fat being eaten and thin starving; inheritors of genes become obese in toxic (obesigenic) environment
interaction of environmental and genetic variance in BMI
healthy environment vs toxic environment, genetic resistance similar but genetically prone increases massively in healthy environment