Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Genetics and Neoplasia > GN 1.5.1 Clinical Correlations Huntington Disease > Flashcards

GN 1.5.1 Clinical Correlations Huntington Disease Flashcards

You may prefer our related Brainscape-certified flashcards:
Biology 101 flashcards
1
Q

What determines the penetrance of the HD?

A

Length of the nucleotide repeat

Short:normal, medium:at risk, large:HD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the main three classes of abnormalities associated w/ HD?

A

Movement (chorea), Cognitive, Psychiatric (depression/anxiety)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the term for the increase in repeats from generation to generation?

A

Anticipation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Once symptomatic, what is the average life expectancy?

A

15 to 18 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the genetic basis of Huntington DZ?

A

Trinucleotide repeat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the mean age of onset?

A

35 to 44 y/o

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the inheritance pattern of HD?

A

Autosomal Dominant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly

Genetics and Neoplasia (35 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions