Glycosaminoglycans:mucopolysaccharides

Question 1

Hyaluronate

Answer 1

D-Glucosamine, D-Glucuronate

Question 2

Chondroitin Sulfate

Answer 2

D-Galactosamine, D-Glucuronate

Question 3

Dermatan Sulfate

Answer 3

D-Galactosamine, L-iduronate/D-Glucuronate

Question 4

Keratin sulfate

Answer 4

D-Glucosamine, none (but contains D-Galactose

Question 5

Heparin Sulfate

Answer 5

D-Glucosamine, D-Glucuronate (major)- L-Iduronate (minor)

Question 6

Heparin

Answer 6

D-Glucosamine, L-iduronate (major)- D-Glucuronate (minor)

Question 7

MPS I H

Answer 7

Hurler, deficient in enzyme alpha-L-Iduronate affects dermatan sulfate and heparin sulfate

Question 8

MPS I S

Answer 8

Scheie, deficient in enzyme alpha-L-Iduronate affects dermatan sulfate and heparin sulfate

Question 9

MPS H/S

Answer 9

Hurler/Scheie, deficient in enzyme alpha-L-Iduronate affects dermatan sulfate and heparin sulfate

Question 10

MPS II (severe)

Answer 10

Hunter (severe), deficient in enzyme Iduronate sulfatase affects dermatan sulfate and heparin sulfate

Question 11

MPS II (mild)

Answer 11

Hunter (mild), deficient in enzyme Iduronate sulfatase affects dermatan sulfate and heparin sulfate