Glycolysis

Question 1

GLUT-1

Answer 1

Blood Brain Barrier, fetal tisue, erythrocytes

Question 2

GLUT-2

Answer 2

Liver, Kidneys, pancrease

Question 3

GLUT-3

Answer 3

Transporter in neurons

Question 4

GLUT-4

Answer 4

Adipocytes, heart/skeletal muscles

Question 5

GLUT-5

Answer 5

Primary transporter for fructose in small intestines

Question 6

GLUT-7

Answer 6

Liver, gluconeogenec tissues, endoplasmic reticulum

Question 7

Fates of Pyruvate

Answer 7

1. Lactate Dehydrogenase
2. Pyruvate Dehydrogenase complex
3. Pyruvate Carboxylase
4. Ethanol Synthesis

Question 8

Lactate Dehydrogenase

Answer 8

important in red blood cell, white blood cells, and others with no mitochondria and in skeletal muscle during intesnse exercise. Physiologically reversible in tissues with a low NADH NAD for example lvier and heart muscle. Located within the cytosol

Question 9

Pyruvate Dehydrogenase Complex

Answer 9

Thiamine PP, lipoic acid, FAD, NAD and CoA serve as coenzymes, source of acetyl CoA for TCA and fatty acid synthesis. Irreversible reaction. Located in mitochondria

Question 10

Pyruvate Carboxylase

Answer 10

Biotin serves as prosthetic group. Activated by acetyl CoA. Replenishes intermediates of the TCA cycle. Provides substrates for gluconeogenesis. Irreversible. Located in mitochondria.

Question 11

Ethanol Synthesis

Answer 11

Occurs in yeast and some bacteria such as intestinal flora. Thiamine pyrophosphate-dependent pathway. Located in the cytosol.