Glutamate, GABA, & Acetylcholine Flashcards
1
Q
Amine
A
Acetylcholine, Dopamine, & Serotonin
2
Q
Amino acid
A
GABA & Glutamate
- Universally expressed
3
Q
Glutamate
A
Major excitatory neurotransmitter
- Results in EPSPs
4
Q
Glutamate Receptors
A
Ionotropic
1. AMPA
2. Kainite
3. NMDA receptors
Metabotropic
1. mGluR
5
Q
GABA
A
Main inhibitory neurotransmitter
- Results in IPSPs
6
Q
Ligands of GABA Receptor
A
- Benzodiazepines (anti-anxiety)
- Barbituates (muscle relaxers)
- Alcohol
- Neurosteroids
7
Q
Acetylcholine
A
- Expressed at Neuromuscular Junction
- Parasympathetic Nervous System
8
Q
Cholinergic Receptors
A
Ionotropic
- Nicotonic
Metabotropic
- Muscarinic
9
Q
Cholinergic Pathways
A
Originates in Basal Forebrain
- Projects into limbic system
(hippocampus)
- Affected by Alzheimer’s Disease
Projects to Brain Stem & Spinal Cord
