Glucose regulation Flashcards
extra glucose
stored as glycogen in liver and muscles
formation of ketone metabolites
high lipolysis and some are expected
- can lead to metabolic acidosis
insulin
pancreatic hormone
- promotes storage formation
glucagon
mobilizes stored glucose
- treats hypoglycemia
pancreas
sits on top of colon in mid stomach region
- in charge of insulin production and secretion
liver
right upper quadrant
- stores glucose
hyperglycemia
increased glucose in blood
- may lead to ketonuria, changes in LOC, metabolic acidosis
s/s of hyperglycemia
thirst, polyuria (lots of pee), sweet smelling urine, ketones in urine,
diabetes complications
stroke, heart attack, peripheral artery disease, retinopothy, glaucoma, diabetic foot, nephropathy, peripheral neuropathy
DM type 1
genetic or due to infection leading to immune reaction where body cannot produce insulin so glucose levels are high
DM type 2
insulin resistance due to pro-inflammatory state caused by obesity or insufficient production
- pancreatic disease, pregnancy, obesity
rapid acting insulin
used for meal time and bolus
long acting insulin
long term used as a background
- never IV
short acting insulin
for meals, issues with hyperglycemia
intermediate acting insulin
for background replacement