Gluconeogenesis: Building up of Glucose Flashcards

1
Q

It is a metabolic pathway by which glucose is synthesized from noncarbohydrate materials

A

GLUCONEOGENESIS

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2
Q

About how many percentages of gluconeogenesis takes place in the liver?

A

90%

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3
Q

Pyruvate to glucose conversion requires the expenditure of?

A

4 ATP and 2 GTP

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4
Q

What are the three irreversible steps in glycolysis that are bypassed by reactions catalyzed by gluconeogenic enzymes?

A
  1. Conversion of pyruvate to PEP via
    oxaloacetate
  2. Dephosphorylation of fructose 1,6-
    bisphosphate
  3. Dephosphorylation of glucose 6-phosphate
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5
Q

Formation of one molecule of glucose from pyruvate requires?

A

4 ATP, 2 GTP, and 2 NADH.

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