glucogensis

Question 1

why is the phosphorylation of pyruvate coupled with the carboxylation (oxalate) and decarboxylation to from phosphoenol pyruvate

Answer 1

this is because the direct phos of pyruvate is highly un favorable due to a very pos DG. coupling this rxn allows for a much smaller pos DG to be adopted by the pathway, where a single mole of ATP can be used to complete the rxn.

decarboxylation drives rxns forward that would otherwise be endergonic

Question 2

is glucogen a favourable pathway

Answer 2

no. it must be coupled with other rxn/enzymes to make it energetically favourable

Question 3

what is the DG of glycoiliss? gluco?

Answer 3

gly= -38kJ/mol

Glu= +22kJ/mol

Question 4

what controls the rate of gluco

Answer 4

the concnetration of lactate and other precourses of glycolysis. these being to increase when glucose is scarce and the body still needs energy.