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PR - ENDOCRINE > GLUCOCORTICOID STEROID > Flashcards

GLUCOCORTICOID STEROID Flashcards

1
Q

What are glucocorticoids?

A

Corticosteroids with potent anti-inflammatory, immunosuppressive and metabolic effects.

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2
Q

High glucocorticoid activity =

A

anti-inflammatory

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3
Q

Dexamethasone/betamethasone

A

Most potent
Long duration of action
Very high glucocorticoid activity
Very little mineralocorticoid activity
Used if fluid retention is a disadvantage e.g. HF
Suitable for high dose therapy

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4
Q

What is the most common PO steroid?

A

Prednisolone/prednisone

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5
Q

Prednisolone/prednisone

A

Significant activity
Long-term disease suppression
Used in acute or severe chronic asthma, COPD, IBD

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6
Q

Deflazacort

A

Deflazacort is derived from prednisolone.
High glucocorticoid activity

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7
Q

Side effects

A

Musculoskeletal - osteoporosis
Endocrine - diabetes
Adrenal suppression
Psychiatric
Infections
GI

Other
Opthalmic
Skin
CNS
Growth restriction

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PR - ENDOCRINE (25 decks)

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