Glucagonoma Flashcards

1
Q

Que células pancreáticas afecta y su localización (+ Dato importante)

A

Células A
Cuerpo y cola
Son grandes >3 cm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Tríada de Glucagonoma

A

Edema migratorio necrotico
Diabetes mellitus
Anemia normo normo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Cuadro clínico con las 6D (Sx glucagonoma)

A

Dermatitis
Diabetes
Deep vein thrombosis
Depresión
Diarrea
Declining weight

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Diagnóstico

A

Hiperglucemia
Hipoproteinemia
Hiperglucagonemia (>150 pg/ml) —> puede estar hasta mil veces más

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Tx de elección

A

Quirúrgico

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Tx farmacológico: Octreotide

A

Reduce los niveles de glucagón
Presentación: solucion inyectable
Dosis: 60-120 mg VSbc cada 28 días
Vida media: 14-33 hrs
Cmax: 6-15 hrs
Efectos secundarios: diarrea, cefalea, insomnio

How well did you know this?
1
Not at all
2
3
4
5
Perfectly