Glomerular Filtration

Question 1

What are the parts of the Nephron in order?

Answer 1

Glomerulus, Bowman’s capsule, proximal tubule, loop of henle, distal tubule, collecting duct

Question 2

What is the most important determinant of GFR?

Answer 2

renal blood flood, but also aterial pressure and renal vascular resistance but they can be regulated by the contraction and dialition of afferent and efferent arterioles

Question 3

If BP falls

Answer 3

afferent arteriole dialates

Question 4

If BP rises

Answer 4

afferent arteriole contricts

Question 5

What does angiotensin 2 do, in terms of low blood pressure?

Answer 5

contricts efferent arteriole, so that GFR is not reduced

so if someone has hypotension, they would still be able to have normal GFR due angiotension 2

Question 6

what does prostaglandins do in terms of low blood pressure

Answer 6

dilates afferent arteriole

Question 7

What are renal constrictors?

Answer 7

Aniotensin 2 - efferent arteriole only

catechlamine

Question 8

What are renal vasodialtors

Answer 8

prostaglandins
AN
pregnancy
high protein diets

Question 9

GFR =

Answer 9

UV * Ucreat/Pcreat

Question 10

Filtration =

Answer 10

GFR * plasma concenttration

Question 11

Excretion =

Answer 11

Urine flow rate * urine concenttration

Question 12

GFR =inverse of

Answer 12

1/Pcreat same as 1/serum creatinine

Question 13

lower the plasma creatinine, the higher the

Answer 13

GFR