Global Health: Non-infectious disease (CVD) Flashcards

1
Q

What three factors make up epidemiological transition?

A

Time, person and place

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2
Q

Why is cardiovascular disease prevalence increasing?

A

Smoking and diet

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3
Q

Why might their be reduced infectious disease prevalence?

A

Better hygiene

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4
Q

What is one characteristic that can influence CHD?

A

Age, sex (lower in women), ethnicity (higher in afro-caribbean by 2000)

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5
Q

How is CVD distributed globally?

A

In America 1/3 of deaths due to CVD, in Africa it was 10% and Europe it was 60% (2010)

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6
Q

How can we determine whether CVD is due to genetics or environmental influence?

A

A suitable trial for this would to be to study migrants with the same ancestry/ethnic background

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7
Q

What are the established risk factors for CHD?

A

blood cholesterol, high BP, smoking, body weight and reduced physical activity

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8
Q

Why does blood pressure increase risk in ‘gradiential way’?

A

For every unit increase in blood pressure/ cholesterol level, the level of CHD increases

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9
Q

Describe the global trend in CVD

A

Deaths from CVD are predicted to be relatively stable in high income countries from 2004-2030, but these rates are predicted to increase for middle and low-income countries (the same trend follows cancer)

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10
Q

After what age does the number of deaths from CVD usually decrease and why

A

80 because most people die after this age

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11
Q

Which ethnicity has higher CVD rates?

A

Afro-caribbeans

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12
Q

How common is river blindness?

A

Not very common, going towards elimination (?)

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13
Q

Which 2 drugs are used to treat helminth infections?

A

Albendazole and Mebendazole

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14
Q

What drug is used to treat onto and LF?

A

Mectizan

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15
Q

Roughly how many deaths caused by schistosomiasis in Africa and how many infected individuals?

A

250 000 deaths and 250 million infected (?)

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16
Q

What is the vector of onchocerciasis?

17
Q

What is the vector of LF?

A

Mosquitoes

18
Q

Which countries has increasing rates of CHD deaths?

A

East Europe

19
Q

Why is serum cholesterol not a good indicator for CVD?

A

poor ability to discriminate between cases and non-cases of heart disease (this is because not only Cholesterol levels cause CHD as this is a multifactorial disease)

20
Q

What can cross sectional studies not do?

A

Find association between putative risk and outcome

21
Q

Does QOF use patient feedback on social media?

22
Q

Why is cervical cancer screening carries out in women aged 25 and above?

A

Cervical abnormalities in younger women do no always progress to cancer

23
Q

Why do children need to be dewormed?

A

Worms cause malnutrition and can cause stunted growth

24
Q

What is PICO?

A

The PICO process is a technique used in evidence based practice to frame and answer a clinical or health care related question.The PICO framework is also used to develop literature search strategies. The PICO acronym stands for population/ patients, intervention, control and outcome.

25
Why do MA give more weight to larger studies than smaller studies?
Larger studies have more accurate effect estimate than smaller studies
26
What is lead time bias?
Lead time is the length of time between the detection of a disease and its usual diagnosis. Diagnosing a disease earlier does not automatically make patients live longer — they merely live for a longer time with the disease ‘label'. Put another way, survival appears longer because the ‘disease clock' starts earlier.