Global health Flashcards

1
Q

what are the top 5 causes of under 5 mortality GLOBALLY

A
Preterm birth complications
Pneumonia
Intrapartum-related complications
Diarrhoea
Neonatal sepsis
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2
Q

what are the top 5 causes of under 5 mortality in AFRICA

A
Diarrhoea
Pneumonia
Malaria
Preterm birth complications
Intrapartum-related complications
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3
Q

what is the definition of under 5 mortality rate

A

Probability of a child born in a specific year or period dying before reaching the age of 5

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4
Q

what is the definition of infant mortality rate

A

Probability of a child born in a specific year or period dying before reaching the age of 1

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5
Q

what is the definition of a live birth

A

Live birth = Any sign of life after birth irrespective of gestation

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6
Q

how can HIV be transmitted from mum to baby

A

pregnancy
delivery
breastfeeding

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7
Q

how can you prevent the transmission of HIV from mum to baby

A

Maternal lifelong antiretroviral treatment
Screen for and treat other STDs, especially herpes
Infant prophylaxis for 6 weeks

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8
Q

when should you test a child for HIV if the mum has it

A
at birth
6 wks
9 months
18months
6wks after cessation of breastfeeding
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9
Q

who should be offered counselling/testing with regards to HIV

A

ALL in countries with generalized HIV epidemics (prevalence over 1% in pregnant women)
ALL exposed infants at birth
Any infant child with any suspicion of HIV

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10
Q

what are the diagnostic tests of HIV

A

18 months of age: virological PCR for HIV DNA or RNA

>18 months: serological rapid antibody test

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11
Q

how is HIV staged

A

Clinical staging = 1-4

Immunological staging = CD4 count

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12
Q

what is the treatment for HIV

A

Highly active antiretroviral therapy (HAART)

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13
Q

what is Highly active antiretroviral therapy (HAART)

A

two NRTRIs + one NNRTI or protease inhibitor

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14
Q

what is a NRTRI, give an example

A

nucleoside reverse transcriptase inhibitor

e.g. abacavir and lamivudine

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15
Q

what is a NNRTI, give an example

A

non-nucleosdie reverse transcriptase inhibitors

e.g. efavirenz

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16
Q

give an example of a protease inhibitor

A

kaletra

17
Q

when would a protease inhibitor be used

A

<3 yrs old

18
Q

when would a NNRTI be used

A

<3 yrs old

19
Q

what are the side effects of HAART

A

Headache, nausea, liver toxicity, hypersensitivity reactions, strange dreams, immune reconstitution inflammatory syndrome (IRIS)

20
Q

what should be treated first TB or HIV

A

TB

21
Q

what is the treatment ofimmune reconsitution inflammatory syndrome (IRIS)

A

NSAIDs

22
Q

what is the treatment for malaria

A

artemisinin-based combination therapy (ACT) for 3 days

23
Q

what is the treatment for severe malaria

A

IM or IV arsenate until they can tolerate oral

24
Q

when should prevention be given

A

infants in high transmission areas

25
Q

what are the signs of severe malnutrition

A

Mid-arm circumference <115mm

Weight for height

26
Q

what are the 4 NON-COMMUNICABLE diseases responsible for a majority of deaths

A

Cardiovascular diseases
Cancers
Diabetes
Chronic respiratory diseases

27
Q

what are the 4 behavioural risk factors of ON-COMMUNICABLE diseases

A

Tobacco use
Harmful use of alcohol
Insufficient physical activity
Unhealthy diet/obesity