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PHRM844 > Glaucoma pt. 2 > Flashcards

Glaucoma pt. 2 Flashcards

1
Q

Open vs close angle glaucoma

A

Open-angle: obstructed drainage canal
Closed-angle: pressure pushes iris against cornea

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2
Q

OA Glaucoma risk factors

A

Age/race
Corea thickness
Steroid use
HTN
Diabetes or sickle cell

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3
Q

OA Glaucoma symptoms

A

No symptoms in early stages
Patchy blind spots
Difficulty in central vision

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4
Q

OA Glaucoma diagnosis

A

Measure IO pressure
Vision loss assessment
Test for optic nerve damage
Measure cornea thickness
Inspect drainage canal

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5
Q

Open-angle tx

A

Beta blockers and carbonic anhydrase (incr outflow)

Prostaglandin analogs, cholinergics, rho kinase inhibitors (decr production)

Alpha-2 agonists (both MOA)

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6
Q

Prostaglandin analogs

A

MOA: incr outflow
SEs: eyelash increase, darkening area
AEs: blurred vision, stinging, light sensitivity

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7
Q

Prostaglandin drugs

A

Latanoprost
Bimatoprost
Travoprost
Tafluprost

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8
Q

Beta blockers

A

MOA: decr production
Contra: sinus bradycardia, heart related conditions
AEs: blurred vision, stinging, bradycardia, breathing problems

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9
Q

Beta blocker drugs

A

Betaxolol
Timolol
Carteolol
Levobunolol

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10
Q

Alpha-2 agonists

A

MOA: incr outflow and decr production
Warning: CNS depression
AEs: blurred vision, dry eyes, xerostomia, sedation/confusion

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11
Q

Alpha-2 agonist drugs

A

Aprachlonidine
Brimonidine + Timolol + Brinzolamide
Brimonidine

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12
Q

Carbonic anhydrase inhibitors

A

MOA: decr production
Warning: sulfonamide allergy
AEs: blurred vision, taste disturbances, confusion, photosensitivity

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13
Q

Carbonic anhydrase inhibitor drugs

A

Dorzolamide + Timolol
Brinzolamide + Brimonidine
Acetazolamide
Methazolamide

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14
Q

Rho kinase inhibitors

A

MOA: incr outflow
AEs: burning, corneal disease, hemorrhage and hyperemia

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15
Q

Rho kinase inhibitor drugs

A

Netarsudil + Latanprost

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16
Q

Cholinergics

A

MOA: incr outflow
Warnings: hx of retinal detachment or corneal abrasion
AEs: corneal clouding, pupil constriction, hypotension, cramps

17
Q

Cholinergic drugs

A

Carbachol
Pilocarpine

18
Q

Turquoise cap

A

Prostaglandin analogs

19
Q

Purple cap

A

Alpha adrenergic agonists

20
Q

Orange cap

A

Carbonic anhydrase inhibitors

21
Q

Red cap

A

Mydriatics and cycloplegics (dilating eye drops)

22
Q

Tan ap

A

Antibiotics

23
Q

Dark blue cap

A

Beta blocker combinations

24
Q

Yellow cap

A

Beta blockers

25
Q

White cap

A

Topical anesthetics AND otc products

26
Q

CA glaucoma symptoms

A

Severe HA or blurred vision
Severe pain or halos
N/V or redness
Cloudy corneas

27
Q

Closed-angle tx

A

Hyperosmotic agents (mannitol, glycerin)
Iridotomy surgery

28
Q

Medications incr IO pressure

A

Anticholinergics
Topiramate
Chronic steroids
Decongestants
Antidepressants

PHRM844 (16 decks)

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