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From Flashcardlet > Glaucoma: Introduction > Flashcards

Glaucoma: Introduction Flashcards

0
Q

juxtacanalicular network

A

identify the normal site of greatest resistance to aqueous outflow

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1
Q

a group of diseases that have in common a characteristic optic neuropathy with associated visual field loss for which elevated IOP is one of the primary risk factors

A

define glaucoma

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2
Q

juxtacanalicular network

A

generally understood to be the site of pathology in primary glaucoma

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3
Q

opitc disc, visual field

A

Of these three: optic disc, visual field, IOP, which two can be suspicious and still maintain a diagnosis of glaucoma suspect and not frank glaucoma?

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4
Q

most frequent cause of nonreversible blindness in blacks

A

superlative statistic for glaucoma

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5
Q

morning

A

time of day during which IOP TYPICALLY peaks

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6
Q

age, race, decreased corneal thickness, increased IOP, family history

A

FIVE solid risk factors for POAG

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7
Q

increased diurnal IOP variation, diabetes, myopia

A

THREE possible but not proven risk factors for POAG

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8
Q

sex, hypertension, vascular disease

A

THREE controversial risk factors for POAG

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9
Q

3.5

A

In the Baltimore Eye Survey, what was the relative prevalence of glaucoma among whites in their 8th decade versus whites in the 5th decade

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10
Q

7.4

A

In the Baltimore Eye Survey, what was the relative prevalence of glaucoma among blacks in their 8th decade versus whites in the 5th decade

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11
Q

increased disc size, thinner corneas, higher IOPs

A

three hypothesized reasons for increased prevalence of POAG among blacks

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12
Q

more screening

A

what might confound a connection between diabetics and higher rates of POAG observed?

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13
Q

Inuits

A

population with the highest incidence of PACG

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14
Q

asians-whites-blacks

A

list these populations by risk of PACG: blacks, asians, whites (DASHES)

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15
Q

3

A

relative risk of women having PACG

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16
Q

age, race, gender, hyperopia, family history

A

four risk factors for PACG

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17
Q

10%

A

prevalence of POAG among siblings of patients with glaucoma

18
Q

TIGR/MYOC

A

The first open-angle glaucoma gene, primarily associated with JOAG, but mutated in 3% of POAG cases

19
Q

TIGR/MYOC

A

gene that may be implicated in IOP response of certain individuals to steroid therapy

20
Q

GLC1A

A

TIGR/MYOC locus

21
Q

myocilin

A

TIGR/MYOC gene product

22
Q

GLC1B, GLC1E

A

two loci associated with normal tension glaucoma

23
Q

optineurin

A

GLC1E gene product

24
Q

GLC1C, GLC1D

A

two loci associated with POAG (high-pressure)

25
Q

GLC3A, GLC3B

A

two congenital glaucoma loci

26
Q

preperimetric glaucoma

A

new visual field testing modalities hope to catch this group of patients

27
Q

combined mechanism glaucoma

A

the major member of this group in glaucoma includes patients who have been successfully treated for PACG but continue to have elevated IOP

28
Q

1.86%

A

incidence of POAG among patients over the age of 40

29
Q

visual field < 20 degrees

A

the more common cutoff of legal blindness achieved by glaucoma sufferers

30
Q

Barbados Eye Study

A

this study documented the highest prevalence of glaucoma (7% in patients over 40) among its population

31
Q

Rotterdam Study

A

this study documented a meager prevalence of glaucoma (0.8% in patients over 40 years) among its population

32
Q

15

A

if you are over 40, your risk of blindness from glaucoma is increased by this proportion if you are black versus white

33
Q

age, African ancestry, visual field severity, cup-disc ratio, central corneal thickness

A

name the seven risk factors for glaucomatous progression identified in the OHTS

34
Q

false

A

TRUE or FALSE: hypertension is a risk factor for glaucomatous progression

35
Q

AGIS, OHTS

A

two studies that found T2DM to be protective in risk of progression of glaucomatous damage

36
Q

overnight

A

when does IOP peak for most patients

37
Q

age

A

the only PACG risk factor that parallels a POAG risk factor

38
Q

Finnish Twin Cohort Study

A

study that supports a genetic component for glaucoma

39
Q

tritanomaly

A

color vision change in glaucoma

40
Q

contrast sensitivity

A

though Snellen acuity is preserved until late, this may be lost early in glaucoma

41
Q

60-80%

A

POAG represents this percentage of adult glaucomas

42
Q

3x

A

relative risk of POAG with myopia

43
Q

access of vasocative amines to optic nerve head

A

theorized role of peripapillary atrophy in glaucoma

From Flashcardlet (61 decks)

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