Glaucoma Flashcards
What causes glaucoma?
Optic nerve damage due to increased intraocular pressure due to blockage in aqueous humour escaping the eye
What causes open angle glaucoma?
Gradual increase in resistance to aqueous flow through the trabecular meshwork causing increased pressure
What causes closed angle glaucoma?
Iris bulges forward and blocks off trabecular meshwork from anterioir chamber so aqueous humour cannot drain away.
Whats the normal passage of aqueous?
Produced by ciliary bodies > around lens under iris > anterior chamber > trabecular meshwork > canal of Schlemm > general circulation
What does increased pressure cause?
Cupping of optic disc
What are risk factors for open angle glaucoma?
Age FH Black Myopia (nearsightedness) Sun exposure Smoking
What field of vision does glaucoma affect?
Peripheral- causes tunnel visoin
How does open angle glaucoma present?
Fluctuating onset pain, headaches, blurred vision and haloes around lights, worse at night
How is pressure measured?
Goldmann applanation tonometry
Visual fields also need to be assessed
What pressure is treatment started at?
24mmHg
What is first line treatment open angle?
Lantanoprost PG analogue
Increase outflow
What are side effects of fist line treatment open angle
Eyelash growth
Eyelid pigmentation
Iris browning
What are other treatment options for open angle glaucoma?
BB Timolol (reduce aqueous produciton
Carbonic anhydrase inhibitors (Dorzolamide)
Sympathomimetics- Brimonidine
Surgery
What operation is done in closed open angle glaucoma?
Trabeculectomy- new channel created
What are risk factors for closed angle glaucoma?
Age FEMALE FH CHINESE/EAST ASIAN Short sighted Sun exposure and smoking Oxybutynin and Solifenacin Tricyclics