GIT inflammation

Question 1

What is Irritable Bowel Syndrome

Answer 1

○ Chronic, relapsing abdominal pain, bloating and changes in bowel habits
○ Gross and microscopic changes are minimaal and hence must be diagnosed on clinical symptoms

Question 2

What are the two types of Inflammatory Bowel Disorders

Answer 2

Chron’s Disease and Ulcerative Colitis

Question 3

What is the distribution of Chron’s Diease

Answer 3

Can occur through any region of the GIT, intermitantly and doesn’t have to becontinuous and inflammation through the mucosa and submucosa

Question 4

What is the distribution of ulcerative colitis

Answer 4

Typically occurs the colon in a continuous fashion and is a transmural inflammation of the gut wall

Question 5

What is the ditribution of Coeliac’s Disease

Answer 5

• Is typically seen in the last proportion of the Duodenum and the proximal jejunum where the highest concentration of food is located
• Histologically the affected areas have villous atrophy, cyrpt hyperplasia and intraepithelial infiltration