Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

perio exam 2 > gingival lesions of systemic origin: Mucocutaneous disorders > Flashcards

gingival lesions of systemic origin: Mucocutaneous disorders Flashcards

1
Q

what is the most common mucocutaneous disease?

A

Lichen planus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is the prevalence of lichen planus?

A

0.1-4%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Skin lesions of lichen planus are characterized by papules with white striae, known as ___________

A

(Wickham striae)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

_______ is the most common symptom of lichen planus

A

itching

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

T/F: lichen planus skin lesions disappear after a few months but oral lesions stay for years

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what are the common clinical characteristics of oral lichen planus?

A

white papules and white striation which often form reticular patterns, usually of bilateral occurrence.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is a papule? a plaque? a bulla?

A

Papula= a small, inflammatory, congested spot on the skin; a pimple

Plaque= A patch on the skin or on a mucous surface

Bulla= A large blister or skin vesicle filled with fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is meant when a lesion is described as “reticular”? what about “ulcerative”?

A

Reticular= Mesh; in the form of network

Ulcerative= Affected with an ulcer; open sore or lesion of the skin or mucosa accompanied by sloughing of inflamed necrotic tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what lichen planus lesion forms are associated with symptoms?

A

Atrophic, ulcerative, bullous forms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

T/F: ular, reticular, plaque-like lesion forms are generally asymptomatic in Lichen plans

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what are the microscopic characteristics of Oral Lichenoid Lesions?

A

is a subepithelial, band-like accumulation of lymphocytes and macrophages characteristic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what causes the accumulation of lymphocytes and macrophages in oral lichnoid lesions?

A

a type IV hypersensitivity reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is the most important part of treating oral lichnoid lesions?

A

Most of important of part of the treatment is an atraumatic meticulous plaque control

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

T/F: Fibrin in the basement membrane, and deposits of IgM, C3, C4, and C5 are characteristic of OLP

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is a Pemphigoid?

A

A group of disorders in which autoantibodies migrate towards components of the basement membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what is the result of pemphigoid?

A

result in detachment of the epithelium from the connective tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Pemphigoid is characterized by autoantibody reactions against ________ and __________ components.

A

hemidesmosome and lamina lucida components.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what is benign mucous membrane pemphigoid (BMMP)?

A

a pemphigoid in which only mucous membrane are affected

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Cicatricial pemphigoid is also used to describe subepithelial bullous disease limited to the ________ or _______

A

mouth or eyes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

what is the main manifestation of BMMP?

A

desquamative lesions of the gingiva presenting intensely erythematous attached gingiva

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

which type of pemphigoid is associated with scarring?

A

cicatricial

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

name the 3 types of pemphigoids

A
  • Bullous
  • Benign Mucous Membrane
  • Cicatricial (Scar formation)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

what is the “Nicholsky sign”? (related to pemphigoids)

A

Rubbing of the gingiva creates bulla formation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

how is BMMP (and other pemphigoids) treated?

A

Plaque removal with daily use of chlorhexidine and/or topical corticosteroid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
what are the lesions formed by Pemphigus vulgaris?
Formation of intraepithelial bullae in skin and mucous membranes
26
T/F: Pemphigus vulgaris is strongly related to genetics
TRUE Jewish and Mediterranean decent
27
what are the physical symptoms of pemphigus vulgaris?
Painful desquamative lesions, erosions or ulcerations. Chronic course with recurrent bulla formation
28
Acantholysis (due to destruction of desmosomes) is a histological sign for what condition?
pemphigus vulgaris
29
in a patient suffering from pemphigus vulgaris, there will be circulating autoantibodies against ________________
interepithelial adhesion molecules
30
T/F: in pemphigus vulgaris, there will be elevated pericellular epithelial deposits of IgG and C3
true
31
what is Lupus erythematosus?
Autoimmune connective tissue disorders in which autoantibodies form to various CELLULAR constituents
32
what are the characteristics of the lesions formed by Lupus erythematosus?
Central atrophic area with small white dots surrounded by irradiating fine white striae with a periphery of telangiectasia
33
_________ _______ Lesions can be ulcerated and cannot be differentiated from leukoplakia or atrophic oral lichen planus
lupus erythematosus
34
what are the histological characteristics of lupus erythematosus?
Degeneration of basal cells and increased WIDTH of the basement membrane. Deposits of various Ig.s, C3 and FIBRIN along the basement membrane
35
T/F: lupus erythematosus is associated with degeneration of basal cells and decreased width of the basement membrane
false Degeneration of basal cells and increased width of the basement membrane
36
the ______ forms of lupus erythematosus can be fatal
systemic
37
what are the 2 major forms of lupus erythematosus?
discoid and systemic
38
the _______ form of lupus erythematosus is the mild chronic form which affects skin and mucous membranes
discoid
39
T/F: antimetabolite drugs used for immunsuppresion in the treatment of autoimmune and other diseases may cause ulcerations
true
40
Swelling, ulceration, petecchia and erythema of gingiva are all found in patients with ________
leukemia
41
_____% of patients with acute leukemia had oral signs of leukemia
69
42
Fibroma/ focal fibrous hyperplasia is due to the _______ processes of periodontal soft tissues
reactive
43
Sessile, well-circumscribed smooth-surfaced nodules are characteristics of what type of lesion?
fibromas & focal fibrous hyperplasia
44
what are the characteristics of Calcified fibroblastic granulomas?
- Often reddish and ulcerated reactive lesion - Fibrous proliferation in which bone- or cementum-like hard tissue is formed - Highly cell-rich areas below ulcerated sites
45
what is the differential diagnosis of a calcified fibroblastic granuloma?
Pyogenic granuloma
46
what clinical signs are associated with Pyogenic granuloma?
- Ulcerated - Reddish or bluish, sometimes lobulated, sessile or pedunculated. Bleeding is common - Highly vascular with chronic inflammatory cells
47
what is a differential diagnosis for pyogenic granulomas?
Pregnancy tumor
48
characteristics of Peripheral giant cell granulomas:
- can occur anywhere on the gingival mucosa - Pedunculated (has a stalk), sessile (broad base), red or purple, commonly ulcerated - Focal collection of multi-nucleated osteoclast-like giant cells - lesions probably originate from the periodontal ligament
49
what is the differential diagnosis for peripheral giant cell granulomas?
focal fibrous hyperplasia
50
name all the periodontal tumors associated with REACTIVE processes of periodontal SOFT tissues:
1) Fibroma/ focal fibrous hyperplasia 2) Calcified fibroblastic granuloma 3) Pyogenic granuloma 4) Peripheral giant cell granuloma
51
Periapical cemental dysplasia is a ______ process of periodontal ______ tissues
Reactive processes of periodontal hard tissues
52
characteristics of periapical cemental dysplasia:
- Fibrous-osseous cemental lesions - Tooth is usually vital. - Usually no symptoms - Periapical bone is replaced by cellular fibroblastic tissue through a cementoblastic phase
53
what is the differential diagnosis for Periapical cemental dysplasia
Cemento-ossifying fibroma and fibrous dysplasia
54
T/F: 4-5 different types of papillomas can occur
true
55
what are the physical characteristics of papillomas?
Exophytic, pedunculated or sessile lesions. Reddish/normal or whitish/gray color A granular/moruloid or filiform/digitated surface
56
what is commonly found inside papilloma lesions?
the Human Papilloma Virus
57
characteristics of Verruca vulgaris (a type of papilloma)
- less common in oral mucosa compared to skin - Sessile, exophytic or raised lesion with a whitish surface - Papillomatous surface with hyperkeratinization and elongated rete ridges
58
Peripheral odontogenic tumors are _______ lesions of periodontal soft tissue
benign
59
where are peripheral odontogenic tumors generally found?
Generally detected in the soft tissue around unerupted teeth
60
Ameloblastomas are derived from ____________
odontogenic epithelium
61
T/F: Squamous odontogenic tumors are malignant
false- they are benign
62
Squamous odontogenic tumors are derived from where?
Derived from pdl, presumably from epithelial rests of Malassez
63
A ________________ is a Slow-growing neoplasm forming hard tissue around the apex of a tooth
Benign cementoblastoma
64
what are the general characteristics of Squamous cell carcinomas?
- found in mandible, posterior to the premolars - nodular lesions, often with ulceration and surrounding leukoplakia - Regional lymph-node metastasis is common
65
________________ are usually caused by soft tissue metastasis from lung cancer
Metastasis to the gingiva
66
T/F: Most of the metastasis cases are carcinoma and not sarcoma
true
67
there is a reoccurrence of Kaposi’s sarcoma in what population group?
AIDS patients
68
T/F: Primary malignant lymphoma is rare in the oral cavity
true | only seen in AIDS patients
69
only ____% of osteosarcomas occur in the jaw
7%
70
Swelling, tenderness, pain and loosening of teeth are frequent symptoms of what malignant condition?
Langerhans cell disease (Histiocytosis X)
71
name the 5 cysts of the periodontium
1- Gingival cyst 2- Lateral periodontal cyst 3- Inflammatory paradental cyst 4- Odontogenic keratocyst 5- Radicular cyst
72
Deposits of C3, IgG and other Ig.s in the basement membranes are found in what condition?
pemphigoids
73
pemphigoids are caused by _____________ reactions
auto-antibody
74
____________-mediated cell destructive processes may be involved in the pathogenesis of pemphigoids
compliment
75
_____________ is the breakdown of the spinous bridges in epithelium
Acantholysis
76
vascular lesions formed by dilatation of a group of small blood vessels is characteristic of what condition?
lupus erythematous
77
Name the condition with the following characteristics: | Periapical bone is replaced by cellular fibroblastic tissue through a cementoblastic phase
Periapical cemental dysplasia

perio exam 2 (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions