Giardia Flashcards

1
Q

Where is giardia located in the body?

A

Small intestine, adheres in intestinal mucosa

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2
Q

What do giardia trophozoites look like?

A

8 flagella, 2 median bodies, bilaterally symmetrical, 15x10 microns

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3
Q

What does the giardia cyst look like?

A

12 x 6 microns, 2-4 nuclei, 2-4 median bodies, 1-2 axonemes

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4
Q

How does giardia feed?

A

Attaches with sucker disc, feeds by pinocytosis, contact digestion

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5
Q

Where do trophozoites reside?

A

Upper small intestine

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6
Q

Why do trophozoites encyst?

A

Dehydration, pass in feces to be consumed by another host

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7
Q

How does giardia spread?

A

Cysts pass from host, go into environment to be consumed by another host

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8
Q

What is the most common cause of giardia?

A

Drinking infectious surface water, outbreaks due to failure of water treatment

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9
Q

What is the main clinical sign of giardia?

A

Diarrhea, humans also get flatulence and abdominal pain

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10
Q

What are the acute signs of giardia?

A

Foul smelling diarrhea, mucous/greasy appearance, flatulence, rarely hematochezia

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11
Q

What are the chronic signs of giardia?

A

Intermittent diarrhea, weight loss, poor growth, poor appetite

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12
Q

What makes giardia hard to diagnose?

A

Small size, do not float well in sugar/salt, intermittent shedding

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13
Q

What floatation method should be used to diagnose giardia?

A

ZnSO4

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14
Q

What is the best way to diagnose giardia?

A

ANSWER THIS

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15
Q

What other types of tests can be used to diagnose giardia?

A

IFA, Giardia antigen test (works well!), Immunocard STAT, nylon thread test for humans

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16
Q

What is the best way to prevent giardia?

A

Water filtration, water treatment by heat, chlorination, or UV light

17
Q

What is the best way to treat giardia?

A

No approved drugs, metronidizole has low efficacy (still treatment of choice), albendazole has safety issues with dogs, fenbendazole(*** professor recommendation)