GI Tract Flashcards

1
Q

Serosa Characteristics

A
  • Outer layer of CT

- Continuous with the Mesentery

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2
Q

Where is most of the colonic water absorbed?

A

Proximal Colon

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3
Q

Spike potentials

A
  • Slow AP
  • Occur automatically when Membrane pot. Is more positive than -40mv
  • Channels open and close slowly
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4
Q

Factors that DECREASE Saliva production

A
  1. Sleep
  2. Dehydration
  3. Fear
  4. Anticholinergic Drugs
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5
Q

MOA of Peristaltic Contractions

A
  1. ENTERO-Chromaffin cells sense food and release SEROTONIN
  2. Serotonin binds to receptors on Primary efferent Neurons
  3. Initiation of the peristaltic reflex
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6
Q

Actions of Gastrin

A
  1. Stimulates gastric acid secretion by the PARIETAL cells

2. Stimulate MUCOSAL growth

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7
Q

Mucosa Characteristics

A
  • Forms a continuous sheet lining entire GI tract
  • Loose CT with sensory nerves
  • Includes muscularis mucosa
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8
Q

Submucosa Characteristics

A

Incorporates BLOOD vessels and submucosal plexus

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9
Q

What maneuver results in an increased abdominal pressure?

A

Valsalva

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10
Q

Actions of Secretin

A

Stimulates

  1. PEPSIN secretion
  2. Bicarbonate
  3. Pancreatic Growth

Inhibits
1. Gastric Acid secretion by Parietal cells

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11
Q

Saliva is controlled by what CN?

A
  • 7 (Facial)

and

  • 9 (Glossopharyngeal)
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12
Q

Factors that cause Depolarization and Hyperpolarization in GI

A

Dep:

  • Stretching of muscle
  • ACh (parasym)
  • Stimulation of specific GI hormones

Hyp:
- NorEpi
- Epinephrine
(Symp)

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13
Q

What are the official GI hormones?

A
  1. Gastrin
  2. CCK
  3. Secretin
  4. Gastric Inhibitory Peptide (GIP)
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14
Q

Actions of CCK

  • Stimulation
  • Inhibition
A

Stimulates:

  1. Pancreatic enzyme secretions
  2. Bicarbonate secretion
  3. Grown of exocrine pancreas
  4. [Bile] of the gallbladder
  5. Relaxation of the Sphincter of Oddi

Inhibits:

  1. Gastric emptying
  2. Appetite
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15
Q

Where do slow waves originate?

A
  • In the Interstitial cells of CAJAL

- Pacemaker

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16
Q

Actions of GIP

A
  • Stimulates insulin release to bring blood glucose down

- Inhibits gastric acid secretion by parietal cells

17
Q

Where do reflexes from the GI go to?

A

The Prevertebral SYMPATHETIC Ganglia

18
Q

What hormones regulate pancreatic secretions?

A
  1. ACH
  2. CCK
  3. Secretin
19
Q

Factors that INCREASE Saliva production

A
  1. Food in mouth
  2. Smells
  3. Reflexes
  4. Nausea
20
Q

What do Chief Cells secrete?

A

Pepsinogen