Cerebellar To Motor Fxn

Question 1

Loss of Fxn in the Flocculo-Nodular Lobes results in what?

Answer 1

Extreme disturbance of equilibrium and Postural movements

Question 2

Lesions of the Fastigial Nuclei result in what?

Answer 2

TRUNK Ataxia

• Related to Postural activity
• Fibers project onto the Reticular Formation and Vestibular Nuclei *

Question 3

Characteristics of Mossy fibers

Answer 3

• Originate from Mult. Centers in the Brainstem and spinal cord
• Make Multiple Synapse on nuclear cells and results in simple spikes
• Synapse on granule cells in glomeruli

Question 4

Where do Climbing Fibers originate?

Answer 4

Medullary Olives

Question 5

What fibers play a role in monitoring learning

Answer 5

Climbing Fibers

Question 6

Layers of the Cerebellar Cortex from Outermost to Innermost.

Answer 6

• Molecular
• Purkinje
• Granular (Gray matter)

Question 7

What can cause Cerebellum Disorders

Answer 7

1. Genetic
2. Tumor
3. Poisons
4. Head injury
5. Cerebral Palsy
6. MS
7. Stroke
8. Infection

Question 8

Climbing Fibers make Multiple Synapses with what?

Answer 8

Purkinje Cells and Nuclear Cells

Question 9

Fxn of the Reticulo-Cerebellar Tracts

Answer 9

• Info about an INTENDED movement and modifications that must be made

Question 10

Changes that occur when Cerebellum is removed

Answer 10

• Movements are slow to develop
• Force developed is weak
• Movements are slow to turn off

Question 11

Fxn of the Lateral Zone

Answer 11

Associated with the Cerebral Cortex with PLANNING of sequential motor movements

Question 12

T/F: The Cerebellum is essential for Locomotion

Answer 12

False

It is NOT essential

Question 13

Damage to the cerebellum can lead to what?

Answer 13

• Intention tremors
• Slurred Speech (dysarthria)
• Nystagmus
• Ballistic Movements (Dystonia)

Question 14

Vestibulo-Cerebellar Syndrome

Answer 14

• Starts with Nystagmus
• Progress to the Fl. Nodular Lobe
• Vertigo/ Tinitis
• Ataxia
• Fine motor skills are LOST

Question 15

Fxn of the Vermis

Answer 15

Control Muscle movements of:

• Axial body (Head, rig cage, spinal column)
• Shoulders
• Hips

Question 16

Fxn of Purkinje Cells Axons

Answer 16

• Regulates RATE, RANGE, and DIRECTION of Movement
• ALWAYS Inhibitory
• Projects to deep Cerebellum and provides synergy

Question 17

Cells in the Cerebral Cortex

Answer 17

• Granular
• Golgi
• Basket
• Stellate
• Mossy fibers
• Purkinje cells

Question 18

Lesions is the Dentate, Emboliform, and Globose Nucle result in what?

Answer 18

EXTREMITY Ataxia

• Related to Fine manipulative movement
• These Fibers project onto the RED Nucleus*

Question 19

What cells can be excitatory or inhibitory

Answer 19

Stellate

Question 20

Fxn of the Intermediate Zone

Answer 20

• ControlsMuscle CONTRACTIONS in the DISTAL portion of the UPPER and LOWER Limbs
• Enhances Stretch Reflex
• Makes Postural Movements

Question 21

Anatomical organization of the Cerebellum

Answer 21

• Two hemispheres separated by the VERMIS

- Each Hemisphere has intermediate and lateral zones

Question 22

Fxn of the Cortico-Ponto- Cerebellar Tracts. Lesions?

Answer 22

Main Link b/w Cortex and Cerebellum

Lesions = MS Weakness

Question 23

Diff lobes of the Cerebellum

Answer 23

1. Ant.
2. Post.
3. Flocculonodular lobe

Question 24

Cells in the Cerebellar Cortex that are INHIBITORY

Answer 24

• Golgi
• Basket
• Stellate (Sometimes)
• Purkinje
• Utilize GABA*

Question 25

Overall Fxns of the Cerebellum

Answer 25

• Coordinates Movement
• Maintains Balance
• Coordinates Eye movement
• Motor Learning
• Related in Language and Mood

Question 26

Each functional unit is centered on what?

Answer 26

A Purkinje Cell

Question 27

Nuclei that make up the Gray matter in the Cerebellum

Answer 27

Intracerebellar Nuclei

1. Dentate
2. Emboliform
3. Globose
4. Fastigial