Cerebellar To Motor Fxn Flashcards
Loss of Fxn in the Flocculo-Nodular Lobes results in what?
Extreme disturbance of equilibrium and Postural movements
Lesions of the Fastigial Nuclei result in what?
TRUNK Ataxia
- Related to Postural activity
- Fibers project onto the Reticular Formation and Vestibular Nuclei *
Characteristics of Mossy fibers
- Originate from Mult. Centers in the Brainstem and spinal cord
- Make Multiple Synapse on nuclear cells and results in simple spikes
- Synapse on granule cells in glomeruli
Where do Climbing Fibers originate?
Medullary Olives
What fibers play a role in monitoring learning
Climbing Fibers
Layers of the Cerebellar Cortex from Outermost to Innermost.
- Molecular
- Purkinje
- Granular (Gray matter)
What can cause Cerebellum Disorders
- Genetic
- Tumor
- Poisons
- Head injury
- Cerebral Palsy
- MS
- Stroke
- Infection
Climbing Fibers make Multiple Synapses with what?
Purkinje Cells and Nuclear Cells
Fxn of the Reticulo-Cerebellar Tracts
- Info about an INTENDED movement and modifications that must be made
Changes that occur when Cerebellum is removed
- Movements are slow to develop
- Force developed is weak
- Movements are slow to turn off
Fxn of the Lateral Zone
Associated with the Cerebral Cortex with PLANNING of sequential motor movements
T/F: The Cerebellum is essential for Locomotion
False
It is NOT essential
Damage to the cerebellum can lead to what?
- Intention tremors
- Slurred Speech (dysarthria)
- Nystagmus
- Ballistic Movements (Dystonia)
Vestibulo-Cerebellar Syndrome
- Starts with Nystagmus
- Progress to the Fl. Nodular Lobe
- Vertigo/ Tinitis
- Ataxia
- Fine motor skills are LOST
Fxn of the Vermis
Control Muscle movements of:
- Axial body (Head, rig cage, spinal column)
- Shoulders
- Hips
Fxn of Purkinje Cells Axons
- Regulates RATE, RANGE, and DIRECTION of Movement
- ALWAYS Inhibitory
- Projects to deep Cerebellum and provides synergy
Cells in the Cerebral Cortex
- Granular
- Golgi
- Basket
- Stellate
- Mossy fibers
- Purkinje cells
Lesions is the Dentate, Emboliform, and Globose Nucle result in what?
EXTREMITY Ataxia
- Related to Fine manipulative movement
- These Fibers project onto the RED Nucleus*
What cells can be excitatory or inhibitory
Stellate
Fxn of the Intermediate Zone
- ControlsMuscle CONTRACTIONS in the DISTAL portion of the UPPER and LOWER Limbs
- Enhances Stretch Reflex
- Makes Postural Movements
Anatomical organization of the Cerebellum
- Two hemispheres separated by the VERMIS
- Each Hemisphere has intermediate and lateral zones
Fxn of the Cortico-Ponto- Cerebellar Tracts. Lesions?
Main Link b/w Cortex and Cerebellum
Lesions = MS Weakness
Diff lobes of the Cerebellum
- Ant.
- Post.
- Flocculonodular lobe
Cells in the Cerebellar Cortex that are INHIBITORY
- Golgi
- Basket
- Stellate (Sometimes)
- Purkinje
- Utilize GABA*
Overall Fxns of the Cerebellum
- Coordinates Movement
- Maintains Balance
- Coordinates Eye movement
- Motor Learning
- Related in Language and Mood
Each functional unit is centered on what?
A Purkinje Cell
Nuclei that make up the Gray matter in the Cerebellum
Intracerebellar Nuclei
- Dentate
- Emboliform
- Globose
- Fastigial
