Basal Ganglia To Motor Fxn Flashcards
Characteristics of Huntington’s Disease
- Symptomatic around 35yrs
- Severe Dementia
- Motor Dysfunctions
- Flicking Movements of individual muscles
- Inherited
Fxn of the Putamen
Large Subconscious Movements of skeletal muscle
- Learned motor activity
- Overall EXCITATORY
(Increase Motor Activity)
The Basal Nuclei Receives most of its input from the ____ and returns their output to the _____.
Cerebral Cortex
The Putamen Circuit is ____ while the Caudate Circuit is _____.
P
- Direct
C
- Indirect
Lesions in the Striatum
- Release of inhibition
- Results of flicking movements all over body
- Occurs in pts w/ Huntington’s Disease
Fxn of the Caudate Nucleus
Large Subconscious Movements of skeletal muscle
- Planning of Sequential and Parallel Motor Patterns
- Overall INHIBITORY
(Tends to Decrease Motor Activity)
The Fxn of the Basal Nuclei
- Plan and Control Complex patterns of muscle movement
- Controlling relative intensities of separate movements
- directions of movements
- sequencing of multiple successive and parallel movements
Fxn of the Globus Pallidus
Regulates Muscle TONE
Characteristics of Parkinson’s Disease
- Rigidity of much of body muscles
- Involuntary tremors
- Difficulty initiating movement
- Postural inability
- Speech disorders
Two Major Basal Nuclei circuits.
Putamen and Caudate
Lesions in the Basal Nuclei lead to what?
Resting Tremors
Lesions in the Globus Pallidus
- Inability to maintain Postural Support
- Continuous spontaneous movements of the hands, arm, neck and/or face
- Athetosis
Dopamine is Excitatory in the ______ pathway and Inhibitory in the ______ pathway.
E
- Direct
I
- Indirect
Lesions in the Subthalamic Nuclei
- Release of inhibition on the CONTRALATERAL Side
- Flailing movements of an entire limb
- Hemiballismus
Principal role of the Basal Ganglia
- Work with the Corticospinal system to modulate THALAMIC Output to the Motor Cortex
- PLAN and Execute Smooth Movements
