GI Tract

Question 1

Effects of oral cavity bacteria:

Answer 1

Group A streptococci can lead to endocarditis

Question 2

What are coliforms?

Answer 2

Gram -ve organisms of GI
E.g. E.coli

Question 3

What is the major source of colonisation?

Answer 3

Ingestion

Question 4

What is the purpose of shedding mucosal?

Answer 4

Prevent build up of microbial communities

Question 5

Role of bile salt:

Answer 5

Interrupts fat
Damages membranes

Question 6

E. coli variants (3):

Answer 6

Enterophathogenic (EPEC)
Enterotoxigenic (ETEC)
Shiva -toxin-producing (S(V)TEC)

Question 7

How are E.coli variants tagged?

Answer 7

Surface pill, fimbriae and flagella

Question 8

Effects of E.Coli 0157:

Answer 8

Produces toxin causing damage to gut

Question 9

What does Clostridiodes difficile cause?

Answer 9

Poor bowel flora
Antibiotic associated diarrhoea
Can survive treatment due to it being a spore

Question 10

How to treat Clostridiodes difficile:

Answer 10

Stop predisposing antibiotic treatment
Fluid replacement
Vancomycin orally

Question 11

Inflammatory Bowel Disease cause:

Answer 11

Disturbed gut micro biome
Weakened intestinal mucosal barrier