Blood Vessels And The Blood Film Flashcards
How to separate blood
Spin in centrifuge
Components of blood
45% red blood cells
<1% buffy coat (platelets and white blood cells)
55% plasma
Where are clotting factors found?
In the plasma
What is serum?
When clotting factors are removed from plasma
What are erythrocytes?
Red blood cells
RBC structure (4)
Bioconcave discs
7 micro m diameter
No nucleus or organelles
Has a network of flexible cytoskeleton elements
3 types of granulocytes (white blood cells)
Neutrophils
Eosinophils
Basophils
2 types of agranulocytes
Monocytes
Lymphocytes
Composition of granulocytes
Neutrophils - 40-70% of WBC’s
Eosinophils - 5%
Basophils - 5%
Neutrophils function and structure
Phagocytes (when activated)
Single, multi-lobed nucleus
Have acidic granules that stain red and contain hydrolytic enzymes.
Eosinophils function and structure
Bi-lobed nucleus.
Respond to Inflammation
What do hydrolytic enzymes cause
Inflammation
Basophils structure and function
Effector cells in allergic reactions
Have basic granules that stain purple.
Bi-lobed nucleus
Composition of agranulocytes
Monocytes: 1-5%
Lymphocytes: 20-50%
Platelets definition
Cell fragments that play an important role in homeostasis
What are the 3 layers of the arteries?
Tunica intima
Tunica media
Tunica adventitia
What is the tunica intima?
Single layer of squamous epithelial cells supported by the basal lamina and a thin layer of connective tissue
Monocytes structure and function
Precursors of tissue phagocytes (macrophages)
Large kidney bean shaped nucleus
Lymphocytes structure and function
Small spherical nucleus
Basophilc (blue) cytoplasm
Gives rise to plasma cells that secrete antibodies
What is tunica media made of?
Mainly smooth muscle
What is tunica adventitia made of?
Supporting connective tissue
Arteriole structure
1 or 2 layers of smooth muscle in tunica media
Almost no tunica adventitia
Capillaries structure
Endothelial cells and a basal lamina
What are the 3 types of capillaries?
Continuous: No pores
Fenestrated: Small pores
Discontinuous: Large gaps
What is in the tunica media of venules?
Intermittent smooth muscle
What are postcapillary venules made of?
Endothelium
Thin layer of connective tissue
Features of tunica media in veins:
Thin and continuous
B cells function
Give rise to plasma cells that secrete antibodies
T cells function
Many defensive functions
Differentiates in thymus