GI system meds Flashcards

1
Q

G: promethazine

B: Phenergan

A

Classification/Action

phenothiazine; antiemetic, also tx of motion sicknedss; antihistamine, anesthesia and analgesia adjunct

Notes

SE: sedation, anticholinergic effects (dry mouth, blurred vision, constipation, urinary retention); orthostatic hypotension

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2
Q

G: metoclopramide

B: Reglan

A

Classification/Action

antiemetic and GI stimulant (reduces gastric stasis

Notes

SE: generally well-tolerated; drowsiness, limit use to 12 weeks to decrease risk of EPS, NMS (w/incr fevel, muscle rigidity

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3
Q

G: diphenoxylate w/ atropine

B: Lomotil

A

Classification/Action

anti-diarrheal

Notes

Schedule V drug due to opioid composition; limit to 4 doses (1-2 tabs/dose) in 24 hr period

SE: drowsiness, rash; anticholinergic effects

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4
Q

G: biscodyl

B: Dulcolax

A

Classification/Action

laxative, stimulant cathartic

Notes

available in PO and suppository form

SE: anorexia; poss GI cramping, diarrhea

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5
Q

G: magnesium hydroxide

B: Milk of Magnesia

A

Classification/Action

laxative, osmotic cathartic antacid in smaller dose

Notes

due to Mg content not recommended for renal pt; incr fluids to prevent dehydration

SE: loose BM’s

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6
Q

G: psyllium

B: Metamucil

A

Classification/Action

bulk forming laxative

Notes

take w/full cup of water or juice

SE: poss GI cramping; esoph or intestinal obstruction (use with plenty of fluid); loose BMs, flatus

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7
Q

G: docusate sodium

B: Colace

A

Classification/Action

stool softener, surfactant laxative

Notes

may take 2 days for effect

**SE: **

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8
Q

G: aluminum hydroxide

B: Amphojel, AlternaGEL

A

Classification/Action

antacid

Notes

Give 1 hr before or 2 hrs after other meds, between meals and hs

SE: constipation esp with long-term use; hypophostatemia

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9
Q

G: simethicone

B: Gas-X, Mylicon

A

Classification/Action

anti-flatulant

Notes

not recommended for infant colic; no known significant SE

**SE: **

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10
Q

G: ranitidine

B: Zantac

A

Classification/Action

H2 inhibitor; anti-ulcer; for tx of PU, GERD; prevention of stress ulcers

Notes

SE: gen well tolerated; may incr risk of pneumonia as decrease gastric acid causes incr risk of gastric bacterial colonization, spread

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11
Q

G: lansoprazole

B: Prevacid

A

Classification/Action

proton pumpinhibitor; anti-ulcer; preferred for tx of PU, GERD, prevention of stress ulcers

Notes

SE: H/A, nausea, diarrhea, may incr risk of pneumonia as decr gastric acid causes incr risk of gastric bacterial colonization, spread

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12
Q

G: lansoprazole, clarithromycin, and amoxicillin

B: Prevpac

A

Classification/Action

proton pumpinhibitor and anti-infective combination of tx of Helicobacter pylori

Notes

Tx course sually 2 weeks

SE: nausea & diarrhea from the antibiotics

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13
Q

G: sulcrafate

B: Carafate

A

Classification/Action

GI mucosal protectorant; for tx of ulcers, IBD

Notes

Give on empty stomach 1 hour ac and at hs; may give tablet dissolved in 1 oz water as “slurry”

SE: constipation

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14
Q

G: misoprostol

B: Cytotec

A

Classification/Action

Prostaglandin analogue, antiulcer cytoprotective agent; helps prevent NSAID induced gastric ulcer

Notes

SE: N&V, gastric upset, diarrhea, menstrual spotting; contraindicated in pregnancy

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15
Q

G: pancrelipase

B: Pancrease, Viokase

A

Classification/Action

pancreatic enzyme

Notes

taken with meals, snacks

SE: generally well tolerated; poss allergic rex

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16
Q

G: inflixamab

B: Remicade

A

Classification/Action

immunosuppressant, GI anti-inflammatory MAB; tx of IBD (Crohn’s and UC); also for other inflammatory conditions such as RA

Notes

DMARD

SE: H/A, N&V, rash, bone marrow suppression, incr risk of infection (esp URI); alopecia; hepatotoxicity

17
Q

G: mercaptopurine (6MP)

B: Purinethol

A

Classification/Action

immunosuppressant; tx of IBD (Crohn’s &UC); anti-neoplastic antimetabolite in larger doses

Notes

SE: N&V, rash, bone marrow suppression, incr risk of infection hepatotoxicity