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High Yield Pharm unit 6 > GI pharm > Flashcards

GI pharm Flashcards

1
Q

Name the three antacids

A
  1. calcium carbonate
  2. Mg hydroxide or carbonate
  3. aluminum hydroxide
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2
Q

Name the categories of drugs that decrease acid production

A
  1. anticholinergics
  2. antihistamines
  3. proton pump inhibitors
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3
Q

What are the anticholinergics

A

probantheline

atropine

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4
Q

What are the antihistamines

A

cimetidine
ranitidine
famotidine
nizatidine

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5
Q

what are the proton pump inhibitors

A

the “prazoles”

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6
Q

when do you take proton pump inhibitors

A

in the morning w/o other medications - it needs acid activation

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7
Q

which class of drugs can cause rebound acidity so you shouldnt stop them abruptly

A

antihistamines

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8
Q

what are the the categories of drugs that increase mucosal resistance

A
  1. coat ulcer crater
  2. increase mucus and bicarb
  3. eradicate h pylori
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9
Q

what drugs coat the ulcer crater ?

A
  1. bismuth salts

2. sucralfate

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10
Q

which drugs increase mucus production? why are they unique?

A

misoprostol

only effective treatment for NSAID ulcers

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11
Q

what drugs are used to eradicate H pylori

A

bismuth salts
metronidazole, tetracycline, amoxicillin, clarithromycin
PPIs

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12
Q

What drugs treat GERD?

A

reduce acidity - antacids, h2 blockers, PPIs

inc motor tone - metochlopramide, cisapride

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13
Q

What drugs are used for vomiting

A
  1. phenothiazines

2. serotonin antagonists

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14
Q

What drugs are in the phenothiazines? what is their MOA?

A

prechlorperazine
promethazine

-dopamine antagonists

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15
Q

What are the serotonin antagonists used to treat vomiting

A

“setrons”

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16
Q

What classes are used to treat diarrhea

A
  1. anticholinergics-atropine
  2. opioid agonists
  3. colloids - metamucil
  4. pectin - kaopectate
17
Q

which drugs are opioid agonists

A
  1. loperamide
  2. diphenoxylate
  3. codeine sulfate
18
Q

What are the classes of drugs used to treat constipation

A

Strong:

  1. irritants
  2. osmotic cathartics

mild:

  1. bulk forming
  2. lubricating
19
Q

what are the irritants

A
  1. castor oil
  2. senna
  3. bisacodyl
  4. phenopthalein
20
Q

what are the osmotic cathartics?

A
  1. mg citrate
  2. sodium sulfate
  3. milk of magnesia
  4. sodium phosphate
21
Q

what are the bulk forming drugs

A
  1. psyllium seed
  2. methycellulose
  3. sodium carboxymethylcellulose
22
Q

What are the lubricants

A
  1. mineral oil
  2. dioctyl sodium
  3. poloxalkols
23
Q

What are the drugs used to treat acute IBD, explain how they are different

A
  1. sulfasalazine

2. otsalazine - less s/e

24
Q

Which anti-constipation drug subset is used for colonoscopy prep

A

osmotic cathartics

25
Q

What drugs are used for chronic IBD

A
  1. azathioprine - purine analog
  2. corticosteroids
  3. cyclosporine - suppresses T cells
  4. infliximab - anti TNF
  5. antibiotics

High Yield Pharm unit 6 (11 decks)

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