GI immunity Flashcards
1
Q
a Th0 in the gut that binds peptide/MHC in the presence of _____ only turns into a Treg (also called an iTreg)
A
TGFbeta
2
Q
A Th0 in the gut that binds peptide/MHC in the presence of TGfbeta and IL6 (due to damage) will turn into a ______
A
Th1, Th2, or Th17
3
Q
what genetic alleles do u have to have to be at risk for celiacs?
A
HLA-DQ2 and HLA-DQ8
4
Q
what is the epitope that is responded to in celiacs disease
A
gliadin alpha 1
